ArticleThe EMBO journal2017
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.
Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Damage recognition by intestinal stem cells via Draper promotes adult Drosophila midgut regeneration.The EMBO journal · 2026Article
- GDF9, NPHS1, and RET Mark Gastric Neuroendocrine Cells and Their Disruption in a PKA-Driven Gastric Preneoplasia Model.International journal of molecular sciences · 2026Article
- Article
- Pralsetinib-Induced Lymphocytic Colitis.ACG case reports journal · 2026Article
- Age-Related Transcriptomic Changes in the Vermiform Appendix.International journal of molecular sciences · 2025Article
- miR-146b-5p Regulates the Enteric Nervous System Development in Hirschsprung Disease via Targeting RET Pathway.Biochemical genetics · 2025Article
- Glial cell line derived neurotrophic factor (GDNF) induces mucosal healing via intestinal stem cell niche activation.Cell proliferation · 2025Article
- Article
- RET Signaling Persists in the Adult Intestine and Stimulates Motility by Limiting PYY Release From Enteroendocrine Cells.Gastroenterology · 2024Article
- Article
- Small bowel edema and lymphocytic duodenitis as severe reversible gastrointestinal toxicity of selpercatinib inFrontiers in oncology · 2023Article
- MAB21L4 Deficiency Drives Squamous Cell Carcinoma via Activation of RET.Cancer research · 2022Article
- Selpercatinib Treatment of RET-Mutated Thyroid Cancers Is Associated With Gastrointestinal Adverse Effects.The Journal of clinical endocrinology and metabolism · 2022Article
- Aberrant RET expression affects normal mammary gland post-lactation transition, enhancing cancer potential.Disease models & mechanisms · 2022Article
- Insect Gut Regeneration.Cold Spring Harbor perspectives in biology · 2022Review
- RET signaling pathway and RET inhibitors in human cancer.Frontiers in oncology · 2022Review
- Article
- TheInternational journal of molecular sciences · 2021Article
- Acute stress disrupts intestinal homeostasis via GDNF-RET.Cell proliferation · 2020Article
- Ageing, metabolism and the intestine.EMBO reports · 2020Review
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 5 countries.
Funding
Abstract
Expression of the Ret receptor tyrosine kinase is a defining feature of enteric neurons. Its importance is underscored by the effects of its mutation in Hirschsprung disease, leading to absence of gut innervation and severe gastrointestinal symptoms. We report a new and physiologically significant site of Ret expression in the intestine: the intestinal epithelium. Experiments in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.