Evidence map›Paper›PMID 28899891›Full record

Trial reportBMJ open2017

Effect of anesthesia

Qianyu Cui, Yuming Peng, Xiaoyuan Liu, Bo Jia, Jia Dong, Ruquan Han

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03033693 (Study of the Depth of Anesthesia on Postoperative Clinical Outcome in Patients With Supratentorial Tumor), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03033693 nacompletednot on this map

Study of the Depth of Anesthesia on Postoperative Clinical Outcome in Patients With Supratentorial Tumor

TypeinterventionalSponsorBeijing Tiantan HospitalRan2017 to 2019Enrolled1,461ConditionsAnesthesia, Brain Tumor, Supratentorial,OutcomeArmsBispectral index will be targeted at 50, Bispectral index will be targeted at 35
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qianyu CuiDepartment of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yuming PengDepartment of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xiaoyuan LiuDepartment of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Bo JiaDepartment of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jia DongDepartment of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ruquan HanDepartment of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecent studies have shown that deep anaesthesia is associated with poor outcomes. However, no randomised controlled trials have been conducted to test the causality in patients undergoing brain tumour resection. METHODS AND ANALYSIS: DEPTH is a multicenter, randomised, parallel-group, blind trial. The depth of general anaesthesia will be monitored using the bispectral index (BIS). Patients elected for supratentorial tumour resection will be randomly allocated to the deep or the light anaesthesia group in which the target BIS value is 35 or 50, respectively. BIS will be maintained at the target value for more than 90% of the total anaesthesia period. The primary outcome is the disability-free survival rate at postoperative 30 days and 1 year. The secondary outcomes are the mortality and morbidity within 30 days after surgery. ETHICS APPROVAL AND DISSEMINATION: Ethical approval has been granted by the Medical Ethics Committee of Beijing Tiantan Hospital, Capital Medicine University. The reference number is KY2016-059-02. The results of this study will be disseminated through presentations at scientific conferences and publication in scientific journals.

trial registrationNCT03033693.

Indexed as

BrainCraniotomyAdolescentAdultAgedAged, 80 and overAnesthesia, GeneralDisability EvaluationFemaleHumansMaleMiddle AgedPostoperative ComplicationsQuality-Adjusted Life YearsResearch DesignSupratentorial Neoplasmsanesthesiabrain tumoroutcomerandomized controlled trial

Identifiers

PMID28899891
PMCPMC5595190

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.