Evidence map›Paper›PMID 28899889›Full record

ArticleBMJ open2017

Neck circumference and clustered cardiovascular risk factors in children and adolescents: cross-sectional study.

José Castro-Piñero, Alvaro Delgado-Alfonso, Luis Gracia-Marco, Sonia Gómez-Martínez, Irene Esteban-Cornejo, Oscar L Veiga, Ascensión Marcos, Víctor Segura-Jiménez, UP&DOWN Study Group

Erratum issuedOpen access · goldAbstract readValidation Study
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

José Castro-PiñeroDepartment of Physical Education, Faculty of Education Sciences, University of Cádiz, Puerto Real, Spain.
Alvaro Delgado-AlfonsoDepartment of Physical Education, Faculty of Education Sciences, University of Cádiz, Puerto Real, Spain.
Luis Gracia-MarcoChildren's Health and Exercise Research Centre (CHERC), Sport and Health Sciences, University of Exeter, Exeter, UK.
Sonia Gómez-MartínezImmunonutrition Group, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), Madrid, Spain.
Irene Esteban-CornejoDepartment of Physical Education, Sports and Human Movement, Faculty of Teacher Training and Education, Autonomous University of Madrid, Madrid, Spain.
Oscar L VeigaDepartment of Physical Education, Sports and Human Movement, Faculty of Teacher Training and Education, Autonomous University of Madrid, Madrid, Spain.
Ascensión MarcosImmunonutrition Group, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), Madrid, Spain.
Víctor Segura-JiménezDepartment of Physical Education, Faculty of Education Sciences, University of Cádiz, Puerto Real, Spain.
UP&DOWN Study Group
Universidad de Cádiz · ESUniversidad Autónoma de Madrid · ESConsejo Superior de Investigaciones Científicas · ESInstitute of Food Science · ITUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEarly detection of cardiovascular disease (CVD) risk factors, such as obesity, is crucial to prevent adverse long-term effects on individuals' health. Therefore, the aims were: (1) to explore the robustness of neck circumference (NC) as a predictor of CVD and examine its association with numerous anthropometric and body composition indices and (2) to release sex and age-specific NC cut-off values to classify youths as overweight/obese.

designCross-sectional study.

setting23 primary schools and 17 secondary schools from Spain.

participants2198 students (1060 girls), grades 1-4 and 7-10. MEASURES: Pubertal development, anthropometric and body composition indices, systolic and diastolic blood pressure (SBP and DBP, respectively), cardiorespiratory fitness, blood sampling triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), glucose and inflammatory markers. Homoeostasis model assessment (HOMA-IR) and cluster of CVD risk factors were calculated.

resultsNC was negatively associated with maximum oxygen consumption (R2=0.231, P<0.001 for boys; R2=0.018, P<0.001 for girls) and adiponectin (R2=0.049, P<0.001 for boys; R2=0.036, P<0.001 for girls); and positively associated with SBP, DBP, TC/HDL-c, TG, HOMA, complement factors C-3 and C-4, leptin and clustered CVD risk factor in both sexes (R2 from 0.035 to 0.353, P<0.01 for boys; R2 from 0.024 to 0.215, P<0.001 for girls). Moreover, NC was positively associated with serum C reactive protein and LDL-c only in boys (R2 from 0.013 to 0.055, P<0.05).

conclusionNC is a simple, low-cost and practical screening tool of excess of upper body obesity and CVD risk factors in children and adolescents. Paediatricians can easily use it as a screening tool for overweight/obesity in children and adolescents. For this purpose, sex and age-specific thresholds to classify children and adolescents as normal weight or overweight/obese are provided.

Indexed as

Body SizeNeckAdipokinesAdolescentAge FactorsBlood PressureCardiovascular DiseasesChildComplement System ProteinsC-Reactive ProteinCross-Sectional StudiesFemaleHumansInflammationInsulin ResistanceLipidsAdipokinesComplement System ProteinsC-Reactive ProteinLipidsNicotinamide Phosphoribosyltransferaseanthropometry and body compositioncardiometabolic risk and cardiovascular diseaseinflammatory markersneck circumferenceyouth.

Identifiers

PMID28899889
PMCPMC5640146
OpenAlexW2754152594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.