Evidence map›Paper›PMID 28899825›Full record

ArticleArchives of physical medicine and rehabilitation2018

Long-Term Performance and User Satisfaction With Implanted Neuroprostheses for Upright Mobility After Paraplegia: 2- to 14-Year Follow-Up.

Ronald J Triolo, Stephanie Nogan Bailey, Kevin M Foglyano, Rudi Kobetic, Lisa M Lombardo, Michael E Miller, Gilles Pinault

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06527417 (The Effect of Electromyography Triggered Electrical Stimulation on Trunk Balance and Muscle Thickness of Multifidus and Erector Spinae Muscles in Patients With Complete Spinal Cord Injury - A Randomised Controlled Study), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06527417 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Electromyography Triggered Electrical Stimulation on Trunk Balance and Muscle Thickness of Multifidus and Erector Spinae Muscles in Patients With Complete Spinal Cord Injury - A Randomised Controlled Study

TypeinterventionalSponsorAnkara City Hospital BilkentRan2023 to 2024Enrolled15ConditionsSpinal Cord Injury ThoracicArmsNeuro Trac Myo Plus Pro, Trunk eccentric exercises
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. The role of electrical stimulation for rehabilitation and regeneration after spinal cord injury.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ronald J TrioloAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH; Departments of Orthopaedics and Biomedical Engineering, Case Western Reserve University, Cleveland, OH.
Stephanie Nogan BaileyAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH. Electronic address: sbailey@aptcenter.org.
Kevin M FoglyanoAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Rudi KobeticAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Lisa M LombardoAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Michael E MillerAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Gilles PinaultAdvanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Louis Stokes Cleveland VA Medical Center · US

Funding

Automatic Control of Standing Balance with Functional Neuromuscular StimulationR01NS040547 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI AUDU, MUSA L, TRIOLO, RONALD J · 2000 to 2022
$7.2M
NEUROPROSTHESIS PERFORMANCE - NERVE CUFF ELECTRODESR01EB001889 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI TRIOLO, RONALD J, TYLER, DUSTIN J. · 2003 to 2017
$5.9M
Long-term follow-up of implanted lower extremity neuroprosthesesI01RX000398 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI TRIOLO, RONALD J · 2012 to 2015
–
Exploiting Selective Recruitment to Prolong Standing after SCII01RX001039 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI TRIOLO, RONALD J, TYLER, DUSTIN J. · 2015 to 2019
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A neuroprosthesis for seated posture and balanceI01RX001204 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI TRIOLO, RONALD J · 2015 to 2016
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NIBIB NIH HHS R01 EB001889NINDS NIH HHS R01 NS040547RRD VA I01 RX000398RRD VA I01 RX001039RRD VA I01 RX001204RRD VA IK6 RX003844
6 · The paper itself

Abstract

objectiveTo quantify the long-term (>2y) effects of lower extremity (LE) neuroprostheses (NPs) for standing, transfers, stepping, and seated stability after spinal cord injury.

designSingle-subject design case series with participants acting as their own concurrent controls, including retrospective data review.

settingHospital-based clinical biomechanics laboratory with experienced (>20y in the field) research biomedical engineers, a physical therapist, and medical monitoring review.

participantsLong-term (6.2±2.7y) at-home users (N=22; 19 men, 3 women) of implanted NPs for trunk and LE function with chronic (14.4±7.1y) spinal cord injury resulting in full or partial paralysis.

interventionsTechnical and clinical performance measurements, along with user satisfaction surveys.

main outcome measuresKnee extension moment, maximum standing time, body weight supported by lower extremities, 3 functional standing tasks, 2 satisfaction surveys, NP usage, and stability of implanted components.

resultsStimulated knee extension strength and functional capabilities were maintained, with 94% of implant recipients reporting being very or moderately satisfied with their system. More than half (60%) of the participants were still using their implanted NPs for exercise and function for >10min/d on nearly half or more of the days monitored; however, maximum standing times and percentage body weight through LEs decreased slightly over the follow-up interval. Stimulus thresholds were uniformly stable. Six-year survival rates for the first-generation implanted pulse generator (IPG) and epimysial electrodes were close to 90%, whereas those for the second-generation IPG along with the intramuscular and nerve cuff electrodes were >98%.

conclusionsObjective and subjective measures of the technical and clinical performances of implanted LE NPs generally remained consistent for 22 participants after an average of 6 years of unsupervised use at home. These findings suggest that implanted LE NPs can provide lasting benefits that recipients value.

Indexed as

Neural ProsthesesPatient SatisfactionActivities of Daily LivingAdultBiomechanical PhenomenaFemaleFollow-Up StudiesHumansLower ExtremityMaleMiddle AgedParaplegiaPostureRetrospective StudiesSpinal Cord InjuriesSurveys and QuestionnairesElectric stimulationLower extremityNeural prosthesesRehabilitationSpinal cord injuries

Identifiers

PMID28899825
PMCPMC5805660
OpenAlexW2751374926

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.