ArticlePhysiology & behavior2017
The cephalic phase insulin response to nutritive and low-calorie sweeteners in solid and beverage form.
Article in Physiology & behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endocrine Cephalic Phase Responses to Food Cues: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- How oro-sensory exposure and eating rate affect satiation and associated endocrine responses-a randomized trial.The American journal of clinical nutrition · 2020Trial
- Chronic sucralose consumption induces elevation of serum insulin in young healthy adults: a randomized, double blind, controlled trial.Nutrition journal · 2020Trial
- Re-evaluation of sucralose (E 955) as a food additive and evaluation of a new application on extension of use of sucralose (E 955) in fine bakery wares.EFSA journal. European Food Safety Authority · 2026Article
- Sweet stimuli induce cephalic phase insulin release to varying degrees in humans.Physiology & behavior · 2026Article
- Low- or No-Energy Sweeteners and Body Weight Management: Dissecting a "Minor" Effect.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Exploring the impact of artificial sweeteners on diabetes management and glycemic control.Frontiers in nutrition · 2025Review
- Interoceptive inference and prediction in food-related disorders.Genes & development · 2024Review
- Chronic Use of Artificial Sweeteners: Pros and Cons.Nutrients · 2024Review
- Could Insulin Be a Better Regulator of Appetite/Satiety Balance and Body Weight Maintenance in Response to Glucose Exposure Compared to Sucrose Substitutes? Unraveling Current Knowledge and Searching for More Appropriate Choices.Medical sciences (Basel, Switzerland) · 2024Review
- Sugar signals from oral glucose transporters elicit cephalic-phase insulin release in mice.The journal of physiological sciences : JPS · 2023Article
- Early-life influences of low-calorie sweetener consumption on sugar taste.Physiology & behavior · 2023Review
- The elusive cephalic phase insulin response: triggers, mechanisms, and functions.Physiological reviews · 2023Review
- Mastication stimuli regulate the heartbeat rate through rhythmic regulation by the hypothalamic-autonomic system; molecular and telemetric studies in weaning-stage rats.Frontiers in neuroscience · 2023Article
- Use of c-peptide as a measure of cephalic phase insulin release in humans.Physiology & behavior · 2022Article
- Extended Inter-Meal Interval Negatively Impacted the Glycemic and Insulinemic Responses after Both Lunch and Dinner in Healthy Subjects.Nutrients · 2022Article
- The Effect of Artificial Sweeteners Use on Sweet Taste Perception and Weight Loss Efficacy: A Review.Nutrients · 2022Review
- Non-nutritive sweeteners and their impacts on the gut microbiome and host physiology.Frontiers in nutrition · 2022Review
- Cephalic phase insulin release: A review of its mechanistic basis and variability in humans.Physiology & behavior · 2021Review
- Effects of Oro-Sensory Exposure on Satiation and Underlying Neurophysiological Mechanisms-What Do We Know So Far?Nutrients · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The purpose of the study was to examine the role of the cephalic phase insulin response (CPIR) following exposure to nutritive and low-calorie sweeteners in solid and beverage form in overweight and obese adults. In addition, the role of learning on the CPIR to nutritive and low-calorie sweetener exposure was tested. Sixty-four overweight and obese adults (age: 18-50years, BMI: 24-37kg/m
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.