Evidence map›Paper›PMID 28899532›Full record

ArticleSleep medicine2017

The association between Disruptive Mood Dysregulation Disorder symptoms and sleep problems in children with and without ADHD.

James G Waxmonsky, Susan D Mayes, Susan L Calhoun, Julio Fernandez-Mendoza, Daniel A Waschbusch, Brianna H Bendixsen, Edward O Bixler

Abstract read
In one paragraph

Article in Sleep medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Oppositional Defiant Disorder in Autism and ADHD.Journal of autism and developmental disorders · 2025
    Article
  9. Clinical characterization of children and adolescents with ADHD and sleep disturbances.European archives of psychiatry and clinical neuroscience · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
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  15. Article
  16. Review
  17. Review
  18. Edward O. Bixler, PhD: from the Apollo project and chimpanzees to sleep epidemiology.Sleep advances : a journal of the Sleep Research Society · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

James G WaxmonskyDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA. Electronic address: jwaxmonsky@hmc.psu.edu.
Susan D MayesDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Susan L CalhounDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Julio Fernandez-MendozaDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Daniel A WaschbuschDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Brianna H BendixsenDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Edward O BixlerDepartment of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Penn State Milton S. Hershey Medical Center · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
WRITING AND THE DAILY EXPERIENCE OF ILLNESSM01RR010732 · NCRR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LOHSE, BARBARA · 1995 to 2009
$29.8M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Sleep and cardio-metabolic risk factors: a prospective study of adolescentsR01HL097165 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O., LIAO, DUANPING · 2010 to 2013
$2.2M
PREVALENCE OF SLEEP DISORDERED BREATHING IN CHILDRENR01HL063772 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O. · 2001 to 2005
$1.3M
NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NCRR NIH HHS M01 RR010732NHLBI NIH HHS R01 HL063772NHLBI NIH HHS R01 HL097165
6 · The paper itself

Abstract

backgroundMany youth experience persistent irritability and recurrent temper outbursts, conceptualized by DSM-5 as Disruptive Mood Dysregulation Disorder (DMDD). Sleep deprivation impairs emotion regulation which could increase rates of DMDD symptoms, especially in those with preexisting regulatory impairments, as seen with ADHD. However, there has been little examination of the relationship between chronic sleep problems and DMDD symptoms.

methodsAssociations between DMDD symptoms and sleep parameters in children were assessed using parent-report and objective measures of sleep in a general population sample (N = 665) and an ADHD sample (N = 784). Irritability, temper outbursts, sleep problems and other psychological problems were assessed with the Pediatric Behavior Scale. The general population study also completed overnight polysomnography (PSG).

resultsDMDD symptoms were reported in 9.2% of the community sample and 31.4% of the ADHD sample. In both samples, children with DMDD symptoms had significantly higher parent-reported sleep problems than children without DMDD symptoms. Children with sleep problems had significantly higher DMDD scores than children without sleep problems. However, DMDD symptoms were most strongly associated with oppositional behavior. Sleep problems were not a significant contributor. Hyperactivity-impulsivity was most strongly associated with sleep problems, and DMDD was not a significant contributor. Children with and without DMDD symptoms did not differ significantly on any PSG parameter.

conclusionsAssociations between parent-reported sleep problems and DMDD symptoms were due to their shared relationship with other behavioral problems. Therefore, chronic sleep problems do not appear to be a primary source of DMDD symptoms in children with or without ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityChildChronic DiseaseFemaleHumansMaleMood DisordersPolysomnographyRetrospective StudiesSleep Wake DisordersADHDMood dysregulationPolysomnographySleep problems

Identifiers

PMID28899532
PMCPMC7085277
OpenAlexW2593997292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.