ReviewClinical & experimental ophthalmology2018
Structural and functional imaging of aqueous humour outflow: a review.
Review in Clinical & experimental ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Safety and Efficacy of Microhook Ab Interno Trabeculotomy Combined with Cataract Surgery in Older Patients with Glaucoma.Ophthalmology and therapy · 2026Article
- Phacoemulsification with IOL implantation combined with goniosynechialysis and goniotomy in primary angle-closure glaucoma following failed trabeculectomy: short-term effectiveness and safety outcomes.Frontiers in medicine · 2026Article
- Advances of Intraocular Fluid for the Application and Treatment of Uveitis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Current Challenges of Managing Fibrosis Post Glaucoma Surgery and Future Perspectives.Journal of clinical medicine · 2025Review
- Six-Month Outcomes of Goniotomy Performed with a Trapezoidal Dual Blade in Combination with Cataract Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Ciliary body size in chronic angle-closure glaucoma.Scientific reports · 2023Article
- Preclinical Pharmacokinetic Profile of Topical Ophthalmic and Intravenous Delivery of QLS-101, a Novel ATP-Sensitive Potassium Channel Opening Ocular Hypotensive Agent.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2023Article
- Advancements in high-resolution imaging of the iridocorneal angle.Frontiers in ophthalmology · 2023Review
- 'Intraoperative predictors for clinical outcomes after microinvasive glaucoma surgery".PloS one · 2023Article
- Evaluation of neural innervation in the human conventional outflow pathway distal to Schlemm's canal.Experimental eye research · 2022Review
- Prospective 12-month outcomes of combined iStent inject implantation and phacoemulsification in Asian eyes with normal tension glaucoma.Eye and vision (London, England) · 2022Article
- Evaluation of different OCT systems in quantitative imaging of human Schlemm's canal.Scientific reports · 2022Article
- Extracellular matrix gene expression in human trabecular meshwork cells following mechanical fluid flow stimulation.International journal of ophthalmology · 2022Article
- Anterior Segment Optical Coherence Tomography Angiography Following Trabecular Bypass Minimally Invasive Glaucoma Surgery.Frontiers in medicine · 2022Article
- Geometric Model and Numerical Study of Aqueous Humor Hydrodynamics in the Human Eye.Computational and mathematical methods in medicine · 2022Article
- Structural Confirmation of Lymphatic Outflow from Subconjunctival Blebs of Live Human Subjects.Ophthalmology science · 2021Article
- Influence of Chronic Ocular Hypertension on Emmetropia: Refractive, Structural and Functional Study in Two Rat Models.Journal of clinical medicine · 2021Article
- Full circumferential morphological analysis of Schlemm's canal in human eyes using megahertz swept source OCT.Biomedical optics express · 2021Article
- Review
- Latanoprost eye drops induce conjunctival lymphatic vessel development.International journal of ophthalmology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Maintaining healthy aqueous humour outflow (AHO) is important for intraocular cellular health and stable vision. Impairment of AHO can lead to increased intraocular pressure, optic nerve damage and concomitant glaucoma. An improved understanding of AHO will lead to improved glaucoma surgeries that enhance native AHO as well as facilitate the development of AHO-targeted pharmaceuticals. Recent AHO imaging has evolved to live human assessment and has focused on the structural evaluation of AHO pathways and the functional documentation of fluid flow. Structural AHO evaluation is predominantly driven by optical coherence tomography, and functional evaluation of flow is performed using various methods, including aqueous angiography. Advances in structural and functional evaluation of AHO are reviewed with discussion of strengths, weaknesses and potential future directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.