Evidence map›Paper›PMID 28895916›Full record

ReviewInternational journal of molecular sciences2017

MicroRNAs in Different Histologies of Soft Tissue Sarcoma: A Comprehensive Review.

Maria Anna Smolle, Andreas Leithner, Florian Posch, Joanna Szkandera, Bernadette Liegl-Atzwanger, Martin Pichler

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Circulating Biomarkers in Sarcoma.Current oncology reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria Anna SmolleDepartment of Orthopaedics and Trauma, Medical University of Graz, 8036 Graz, Austria. maria.smolle@cbmed.at.
Andreas LeithnerDepartment of Orthopaedics and Trauma, Medical University of Graz, 8036 Graz, Austria. andreas.leithner@medunigraz.at.
Florian PoschDivision of Oncology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria. florian.posch@medunigraz.at.
Joanna SzkanderaDivision of Oncology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria. joanna.szkandera@medunigraz.at.
Bernadette Liegl-AtzwangerInstitute of Pathology, Medical University of Graz, 8036 Graz, Austria. bernadette.liegl-atzwnager@medunigraz.at.
Martin PichlerDivision of Oncology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria. martin.pichler@medunigraz.at.
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soft tissue sarcomas (STS) constitute a rare tumour entity comprising over 50 histological subtypes. MicroRNAs (miRNAs) are short non-protein coding RNA molecules that regulate gene expression by targeting the 3'-untranslated region of messenger RNAs. They are involved in a variety of human diseases, including malignancies, such as endometrial cancer, osteosarcoma, bronchial carcinoma and breast cancer. In STS, various miRNAs are differentially expressed, thus contributing to development, progression and invasion. Therefore, the aim of the present review is to summarise current knowledge on the role of miRNAs in STS. Furthermore, the potential role of miRNAs as diagnostic, prognostic and predictive biomarkers is discussed.

Indexed as

Gene Expression Regulation, NeoplasticBiomarkers, TumorFibrosarcomaHemangiosarcomaHumansLeiomyosarcomaLiposarcomaMicroRNAsNeurilemmomaPrognosisRhabdomyosarcomaRNA, MessengerSarcomaSarcoma, SynovialBiomarkers, TumorMicroRNAsRNA, MessengermicroRNAssoft tissue sarcomatumourigenesis

Identifiers

PMID28895916
PMCPMC5618609
OpenAlexW2754973376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.