Evidence map›Paper›PMID 28895842›Full record

ArticleJournal of the American Society of Hypertension : JASH2017

Adherence to antihypertensive medications and associations with blood pressure among African Americans with hypertension in the Jackson Heart Study.

Mark J Butler, Rikki M Tanner, Paul Muntner, Daichi Shimbo, Adam P Bress, Amanda J Shallcross, Mario Sims, Gbenga Ogedegbe, Tanya M Spruill

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Hypertension : JASH, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Sex-Specific Blood Pressure Thresholds in Middle-Aged Adults.Hypertension (Dallas, Tex. : 1979) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Mark J ButlerDepartment of Population Health, NYU School of Medicine, New York, NY, USA. Electronic address: mark.butler@nyumc.org.
Rikki M TannerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Daichi ShimboDepartment of Medicine, Columbia University Medical Center, New York, NY, USA.
Adam P BressDepartment of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.
Amanda J ShallcrossDepartment of Population Health, NYU School of Medicine, New York, NY, USA.
Mario SimsDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Gbenga OgedegbeDepartment of Population Health, NYU School of Medicine, New York, NY, USA.
Tanya M SpruillDepartment of Population Health, NYU School of Medicine, New York, NY, USA.
New York University · USUniversity of Alabama at Birmingham · USColumbia University Irving Medical Center · USJackson Memorial Hospital · USUniversity of Utah · US

Funding

Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Genetic ancestry and antihypertensive medication responses in African AmericansK01HL133468 · NHLBI · UNIVERSITY OF UTAH · PI BRESS, ADAM P · 2016 to 2020
$787k
Midcareer Investigator Award in Patient-Oriented Research for Dr. Gbenga OgedegbeK24HL111315 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OGEDEGBE, OLUGBENGA G. · 2012 to 2016
$621k
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS K01 HL133468NHLBI NIH HHS K24 HL111315NHLBI NIH HHS K24 HL125704NHLBI NIH HHS R01 HL117323
6 · The paper itself

Abstract

The purpose of this study was to test the association between a self-report measure of 24-hour adherence to antihypertensive medication and blood pressure (BP) among African Americans. The primary analysis included 3558 Jackson Heart Study participants taking antihypertensive medication who had adherence data for at least one study examination. Nonadherence was defined by self-report of not taking one or more prescribed antihypertensive medications, identified during pill bottle review, in the past 24 hours. Nonadherence and clinic BP were assessed at Exam 1 (2000-2004), Exam 2 (2005-2008), and Exam 3 (2009-2013). Associations of nonadherence with clinic BP and uncontrolled BP (systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg) were evaluated using unadjusted and adjusted linear and Poisson repeated measures regression models. The prevalence of nonadherence to antihypertensive medications was 25.4% at Exam 1, 28.7% at Exam 2, and 28.5% at Exam 3. Nonadherence was associated with higher systolic BP (3.38 mm Hg) and diastolic BP (1.47 mm Hg) in fully adjusted repeated measures analysis. Nonadherence was also associated with uncontrolled BP (prevalence ratio = 1.26; 95% confidence interval = 1.16-1.37). This new self-report measure may be useful for identifying nonadherence to antihypertensive medication in future epidemiologic studies.

Indexed as

Drug MonitoringAgedAntihypertensive AgentsBlack or African AmericanBlood PressureBlood Pressure DeterminationFemaleHumansHypertensionLongitudinal StudiesMaleMiddle AgedSelf ReportAntihypertensive Agentsblood pressure controldiastolichypertensiveJHSMedication adherencesystolic

Identifiers

PMID28895842
PMCPMC5603252
OpenAlexW2732344361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.