Evidence map›Paper›PMID 28895298›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2018

Two decades of dendrimers as versatile MRI agents: a tale with and without metals.

Michael T McMahon, Jeff W M Bulte

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. ChemMedChem · 2022
    Review
  16. Polyphosphorhydrazone-Based Radical Dendrimers.Molecules (Basel, Switzerland) · 2021
    Review
  17. CEST MRI trackable nanoparticle drug delivery systems.Biomedical materials (Bristol, England) · 2021
    Review
  18. Dendrimers: A New Race of Pharmaceutical Nanocarriers.BioMed research international · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael T McMahonThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jeff W M BulteThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

Multi-Color Exchange Transfer Imaging of Drug Delivery NanocarriersR01EB015031 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MCMAHON, MICHAEL T · 2011 to 2014
$2.4M
Dual-mode MRI for in vivo sensing of microcapsule stability and biocompatibilityR01DK106972 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2015 to 2018
$1.7M
NIBIB NIH HHS R01 EB015031NIDDK NIH HHS R01 DK106972
6 · The paper itself

Abstract

Dendrimers or dendritic polymers are a class of compounds with great potential for nanomedical use. Some of their properties, including their rigidity, low polydispersity and the ease with which their surfaces can be modified make them particularly well suited for use as MRI diagnostic or theranostic agents. For the past 20 years, researchers have recognized this potential and refined dendrimer formulations to optimize these nanocarriers for a host of MRI applications, including blood pool imaging agents, lymph node imaging agents, tumor-targeted theranostic agents and cell tracking agents. This review summarizes the various types of dendrimers according to the type of MR contrast they can provide. This includes the metallic T

Indexed as

Contrast MediaDendrimersAnimalsCell Line, TumorHumansMagnetic Resonance ImagingMiceContrast MediaDendrimers

Identifiers

PMID28895298
PMCPMC5989322

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.