Evidence map›Paper›PMID 28895292›Full record

ReviewPediatric blood & cancer2018

Pathology and genomics of pediatric melanoma: A critical reexamination and new insights.

Armita Bahrami, Raymond L Barnhill

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric blood & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Observational
  14. Imaging of pediatric cutaneous melanoma.Pediatric radiology · 2019
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Armita BahramiDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID http://orcid.org/0000-0002-8515-2649
Raymond L BarnhillDepartment of Pathology, Institute Curie and Faculty of Medicine, University of Paris Descartes, Paris, France.
Délégation Paris 5 · FRSt. Jude Children's Research Hospital · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

The clinicopathologic features of pediatric melanoma are distinct from those of the adult counterpart. For example, most childhood melanomas exhibit a uniquely favorable biologic behavior, save for those arising in large/giant congenital nevi. Recent studies suggest that the characteristically favorable biologic behavior of childhood melanoma may be related to extreme telomere shortening and dysfunction in the cancer cells. Herein, we review the genomic profiles that have been defined for the different subtypes of pediatric melanoma and particularly emphasize the potential prognostic value of telomerase reverse transcriptase alterations for these tumors.

Indexed as

GenomicsMelanomaNeoplasm ProteinsTelomeraseTelomereAdolescentAdultChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleTelomere HomeostasisNeoplasm ProteinsTelomeraseTERT protein, humanchildhood melanomamelanoma arising in association with large/giant congenital nevipediatric melanomaspitzoid melanoma

Identifiers

PMID28895292
PMCPMC6500729
OpenAlexW2756090597

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.