Evidence map›Paper›PMID 28895099›Full record

ArticleJournal of neurovirology2017

Neurological and multiple organ involvement due to Paracoccidioides brasiliensis and HIV co-infection diagnosed at autopsy.

Sergio Monteiro de Almeida, Thiago H Roza, Gabriel L O Salvador, João C B França, Luine Rosele Renaud Vidal, Meri Bordignon Nogueira, Lubomira Veronica Oliva, Luis Fernando Bleggi Torres, Lucia Helena de Noronha

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PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sergio Monteiro de AlmeidaMedical Pathology Department, Medicine School, Universidade Federal do Paraná, Curitiba, Paraná, Brazil. sergio.ma@ufpr.br.
Thiago H RozaMedical Pathology Department, Medicine School, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Gabriel L O SalvadorMedical Pathology Department, Medicine School, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
João C B FrançaInfectious Diseases Unit, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Luine Rosele Renaud VidalVirology Laboratory, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Meri Bordignon NogueiraVirology Laboratory, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Lubomira Veronica OlivaMedical Pathology Department, Medicine School, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Luis Fernando Bleggi TorresMedical Pathology Department, Medicine School, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Lucia Helena de NoronhaMedical Pathology Department, Medicine School, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Universidade Federal do Paraná · BRHospital de Clínicas Universidade Federal do Paraná · BRPontifícia Universidade Católica do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paracoccidioidomycosis (PCM), caused by Paracoccidioides brasiliensis, is the most prevalent systemic mycosis among immunocompetent patients in Latin America; it is rare in immunocompromised patients. The estimated frequency of central nervous system (CNS) involvement in the HIV/PCM population was 2.5%. We report a case of HIV/P. brasiliensis co-infection, with neurological (NPCM) and multiple organ involvement, indicating a diagnosis of AIDS. PCM diagnosis was established during the autopsy. This is the first described case of HIV/P. brasiliensis co-infection with CNS involvement diagnosed at autopsy. In conclusion, the diagnosis of NPCM is challenging, and it must be considered in the differential diagnosis in HIV-positive patients who reside in or have visited areas in which the condition is endemic and who present with neurological symptoms.

Indexed as

Immunocompromised HostAcute Kidney InjuryAdultAutopsyBrazilCentral Nervous SystemCoinfectionDiagnosis, DifferentialFatal OutcomeHIV-1HIV InfectionsHumansMaleParacoccidioidesParacoccidioidomycosisCentral nervous systemCo-infectionHIVNeuro-paracoccidioidomycosisParacoccidioides brasiliensisParacoccidioidomycosis

Identifiers

PMID28895099
OpenAlexW2755083670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.