Evidence map›Paper›PMID 28895092›Full record

ArticleCognitive, affective & behavioral neuroscience2017

Neural response to evaluating depression predicts perceivers' mental health treatment recommendations.

Anne C Krendl, Brittany S Cassidy

Abstract read
In one paragraph

Article in Cognitive, affective & behavioral neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anne C KrendlDepartment of Psychological and Brain Sciences, Indiana University, 1101 E. 10th St., Bloomington, IN, 47405, USA. akrendl@indiana.edu.
Brittany S CassidyDepartment of Psychological and Brain Sciences, Indiana University, 1101 E. 10th St., Bloomington, IN, 47405, USA.

Funding

Investigating connectivity-based mechanisms for age-related increased prejudiceF32AG051304 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI CASSIDY, BRITTANY SHANE · 2016 to 2018
$134k
American Psychological Foundation 2014 APF Visionary GrantNational Institute of Aging F32AG051304NIA NIH HHS F32 AG051304
6 · The paper itself

Abstract

Nonstigmatized perceivers' initial evaluations of stigmatized individuals have profound consequences for the well-being of those stigmatized individuals. However, the mechanism by which this occurs remains underexplored. Specifically, what beliefs about the stigmatized condition (stigma-related beliefs) shape how nonstigmatized perceivers evaluate and behave toward stigmatized individuals? We examined these questions with respect to depression-related stigmatization because depression is highly stigmatized and nondepressed individuals' behavior (e.g., willingness to recommend treatment) directly relates to removing stigma and increasing well-being. In Study 1, we identified common stigma-related beliefs associated with depression (e.g., not a serious illness, controllable, threatening), and found that only perceptions that depression is a serious condition predicted nondepressed perceivers' willingness to recommend mental health treatment. Moreover, perceivers' beliefs that depression is a distressing condition mediated the relationship between perceived seriousness and treatment recommendations (Study 1). In Study 2, we used fMRI to disentangle the potential processes connecting distress to nondepressed perceivers' self-reported treatment intentions. Heightened activity in the dorsomedial prefrontal cortex (dmPFC)-a region widely implicated in evaluating others-and the ventrolateral prefrontal cortex (vlPFC)-a region widely implicated in regulating negative emotions-emerged when nondepressed perceivers evaluated individuals who were ostensibly depressed. Beliefs that depression is a distressing condition mediated the relationship between dmPFC (but not vlPFC) activity and nondepressed individuals' self-reported treatment recommendations.

Indexed as

Depressive DisorderHealth Knowledge, Attitudes, PracticeSocial PerceptionSocial StigmaAdolescentAdultBrainBrain MappingFemaleHumansJudgmentMagnetic Resonance ImagingMaleNeuropsychological TestsYoung AdultDepressionDorsomedial prefrontal cortexfMRIStigma

Identifiers

PMID28895092
PMCPMC5806511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.