ArticleRadiological physics and technology2017
Influence of Gd-EOB-DTPA on proton density fat fraction using the six-echo Dixon method in 3 Tesla magnetic resonance imaging.
Article in Radiological physics and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Influence of Gadoxetate disodium to the hepatic proton density fat fraction quantified with the Dixon sequences in a rabbit model.Abdominal radiology (New York) · 2024Article
- Influence of Gd-EOB-DTPA on proton-density fat fraction in the liver using chemical shift-encoded magnetic resonance imaging at 3-T.Radiological physics and technology · 2024Article
- A comparison of emulsifiers for the formation of oil-in-water emulsions: stability of the emulsions within 9 h after production and MR signal properties.Magma (New York, N.Y.) · 2022Article
- Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol.Journal of visualized experiments : JoVE · 2018Article
- Influence of Gd-EOB-DTPA on T1 dependence of the proton density fat fraction using magnetic resonance spectroscopy.Radiological physics and technology · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to evaluate whether disodium gadoxetate (Gd-EOB-DTPA) affects proton density fat fractions (PDFFs) during use of the multiecho Dixon (meDixon) method in phantom and simulation magnetic resonance imaging (MRI) studies at 3 T. Fat-water phantoms comprising vegetable fat-water emulsions with varying fat volume percentages (0, 5, 10, 15, 20, 30, 40, and 50) and Gd-EOB-DTPA concentrations (0 and 0.4 mM) were prepared. Phantoms without Gd-EOB-DTPA were defined as precontrast, and those with Gd-EOB-DTPA were defined as postcontrast. All phantoms were scanned with a 3 T MRI system using the meDixon method, and precontrast and postcontrast PDFFs were calculated. Simulated pre and postcontrast PDFFs in the liver were calculated using a theoretical formula. The relationship between PDFFs measured in the pre and postcontrast phantoms was evaluated using linear regression and Bland-Altman analysis. The regression analysis comparing the pre and postcontrast PDFFs yielded a slope of 0.77 (P < 0.001). The PDFFs on the postcontrast phantom were smaller than those on the precontrast phantom. The mean difference between the PDFFs on the pre and postcontrast phantoms was 6.12% (95% confidence interval 3.13 to 9.10%; limits of agreement -0.88 to 13.11%). The simulated PDFF on the postcontrast phantom was smaller than that on the precontrast phantom. We demonstrated that the PDFF measured using the meDixon was smaller on postcontrast than on precontrast at 3 T, if a low flip angle was used. This tendency was also seen in the simulation study results.
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