ArticleLaryngoscope investigative otolaryngology2017
The use of oculomotor, vestibular, and reaction time tests to assess mild traumatic brain injury (mTBI) over time.
Article in Laryngoscope investigative otolaryngology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Use of a Portable 3D Head Mounted Display With Integrated Eye Capture Technology (I-PAS) for the Objectification and Quantification of Signs and Symptoms Associated With the Diagnosis of Mild Traumatic Brain Injury (mTBI)
Standardized Instruments to Provide Diagnostic and Prognostic Information in Mild Traumatic Brain Injury (mTBI)
Who cites it
29 citing papers in PubMed.
- Portable eye-tracking as a reliable assessment of oculomotor, cognitive and reaction time function: Normative data for 18-45 year old.PloS one · 2021Trial
- Eye movements and ocular biomarkers in mild traumatic brain injury: from oculomotor pathophysiology to diagnosis and prognosis.Journal of neurology · 2026Review
- Capacity Versus Performance of Volitional Head Turns After Mild Traumatic Brain Injury.The Journal of head trauma rehabilitation · 2026Article
- Diagnosis of mTBI in an ER Setting Using Eye-Tracking and Virtual Reality Technology: An Exploratory Study.Brain sciences · 2025Article
- Oculomotor, vestibular, reaction time, and cognitive (OVRT-C) responses in 7- to 17-year-old children.Experimental brain research · 2025Article
- Scoping review: Intervention for ocular motor disorders in children and adults with mild traumatic brain injury.Optometry and vision science : official publication of the American Academy of Optometry · 2025Article
- Investigating the Utility of the BrainEye Smartphone Eye Tracking Application and Platform in Concussion Management.Sports medicine - open · 2025Article
- Classification of short and long term mild traumatic brain injury using computerized eye tracking.Scientific reports · 2024Article
- Longitudinal Outcomes of Cumulative Impact Exposure on Oculomotor Functioning in Professional Motorsport Drivers.JAMA network open · 2023Article
- Assessment of balance in people with mild traumatic brain injury using a balance systems model approach.Gait & posture · 2023Article
- A window into eye movement dysfunction following mTBI: A scoping review of magnetic resonance imaging and eye tracking findings.Brain and behavior · 2022Article
- The Non-Concordance of Self-Reported and Performance-Based Measures of Vestibular Dysfunction in Military and Civilian Populations Following TBI.Journal of clinical medicine · 2022Article
- Characterizing the evolution of oculomotor and vestibulo-ocular function over time in children and adolescents after a mild traumatic brain injury.Frontiers in neurology · 2022Article
- Eye Movements in Mild Traumatic Brain Injury: Ocular Biomarkers.Journal of eye movement research · 2022Article
- Normative data for ages 18-45 for ocular motor and vestibular testing using eye tracking.Laryngoscope investigative otolaryngology · 2021Article
- Research Evaluating Sports ConcUssion Events-Rapid Assessment of Concussion and Evidence for Return (RESCUE-RACER): a two-year longitudinal observational study of concussion in motorsport.BMJ open sport & exercise medicine · 2021Article
- Exploring persistent complaints of imbalance after mTBI: Oculomotor, peripheral vestibular and central sensory integration function.Journal of vestibular research : equilibrium & orientation · 2021Article
- Eye movement performance and clinical outcomes among female athletes post-concussion.Brain injury · 2020Article
- A commentary for neuropsychologists on CDC's guideline on the diagnosis and management of mild traumatic brain injury among children.The Clinical neuropsychologist · 2020Article
- Vertical smooth pursuit as a diagnostic marker of traumatic brain injury.Concussion (London, England) · 2020Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this work is to examine the outcomes of a set of objective measures for evaluating individuals with minor traumatic brain injury (mTBI) over the sub-acute time period. These methods involve tests of oculomotor, vestibular, and reaction time functions. This work expands upon published work examining these test results at the time of presentation. STUDY
designThis study is a prospective age- and sex-matched controlled study. MATERIALS AND
methodsThe subject group was composed of 106 individuals with mTBI and 300 age- and sex-matched controls without a history of mTBI. All individuals agreeing to participate in the study underwent a battery of oculomotor, vestibular, and reaction time tests (OVRT). Those subjects with mTBI underwent these tests at presentation (within 6 days of injury) and 1 and 2weeks post injury. These outcomes were compared to each other over time as well as to results from the controls that underwent 1 test session.
resultsSix measures from 5 tests can classify the control and mTBI during Session 1 with a true positive rate (sensitivity) of 84.9% and true negative rate (specificity) of 97.0%. Patterns of abnormalities changed over time in the mTBI group and overall normalized in a subset of individuals at the third (final) testing session.
conclusionsWe describe an objective and effective second generation testing algorithm for diagnosing and following the prognosis of mTBI/concussion. This testing paradigm will allow investigators to institute better treatments and provide more accurate return to activity advice. LEVEL OF EVIDENCE: 3.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.