Evidence map›Paper›PMID 28894820›Full record

ArticleLaryngoscope investigative otolaryngology2017

Indwelling voice prosthesis insertion after total pharyngolaryngectomy with free jejunal reconstruction.

Hirofumi Fukushima, Takeharu Kanazawa, Kazuyoshi Kawabata, Hiroki Mitani, Hiroyuki Yonekawa, Toru Sasaki, Wataru Shimbashi, Akira Seto, Ryousuke Kamiyama, Kiyoshi Misawa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Prosthetic voice rehabilitation after laryngoesophagectomy: surgical and functional outcomes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hirofumi FukushimaDepartment of Head and Neck Surgery.
Takeharu KanazawaCancer Institute Hospital, Japanese Foundation of Cancer Research, Department of Otolaryngology-Head and Neck Surgery Tokyo Japan.
Kazuyoshi KawabataTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Hiroki MitaniTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Hiroyuki YonekawaTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Toru SasakiTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Wataru ShimbashiTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Akira SetoTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Ryousuke KamiyamaTokyo Medical and Dental University Graduate School of Medicine, Division of Head and Neck Tokyo Japan.
Kiyoshi MisawaJichi Medical University, Shimotsuke, Japan, Department of Otolaryngology/Head and Neck Surgery Hamamatsu University School of Medicine Hamamatsu Japan.
Takahiro AsakageDepartment of Head and Neck Surgery.
Tokyo Medical and Dental University · JPHamamatsu University · JPJapanese Foundation For Cancer Research · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTotal pharyngolaryngectomy with free jejunal reconstruction is often performed in patients with hypopharyngeal carcinoma. However, postoperative speechlessness significantly decreases patient quality of life. We investigated whether Provox® insertion could preserve speech after total pharyngolaryngectomy with free jejunal reconstruction. STUDY

designRetrospective chart review.

methodsA total of 130 cases of secondary Provox® insertions after total pharyngolaryngectomy with free jejunal reconstruction were analyzed. Communication outcomes were compared using the Head and Neck Cancer Understandability of Speech Subscale. Outcomes and complications associated with insertion site (jejunal insertion vs. esophageal insertion) and adjuvant irradiation therapy were also evaluated.

resultsProvox® insertion had favorable communication outcomes in 102 cases (78.4%). Neither the insertion site nor irradiation affected the communication outcome. Complications were observed in 20 cases (15.4%). Local infection was the most common complication. Free jejunal insertion, in which the resection range was enlarged, had a lower complication rate than did esophageal insertion, and its complication rate was unaffected by previous irradiation. For all patients, the hospitalization duration and duration of speechlessness were 13.4 days and 14.6 months, respectively. Patients receiving jejunal insertions had a significantly shorter hospitalization duration than did those receiving esophageal insertions. Unlike Provox®2, Provox®Vega significantly reduced the complication rate to zero.

conclusionFor jejunal inserson of a Provox® prosthetic, a sufficient margin can be maintained during total pharyngolaryngectomy and irradiation can be performed, and satisfactory communication outcomes were observed. Provox® insertion after total pharyngolaryngectomy with free jejunal reconstruction should be considered the standard therapy for voice restoration. LEVEL OF EVIDENCE: 4.

Indexed as

complicationHypopharyngeal carcinomaindwelling voice prosthesisresection rangevoice rehabilitation

Identifiers

PMID28894820
PMCPMC5510280
OpenAlexW2589970816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.