Evidence map›Paper›PMID 28894781›Full record

ArticleEmergency (Tehran, Iran)2017

Diagnostic Accuracy of Quick Stick for Identifying Traumatic Patients in Need of Tetanus Prophylaxis; a Cross-sectional Study.

Iraj Golikhatir, Seyed Hossein Montazer, Nabiollah Bagheri, Fatemeh Jahanian, Farzad Bozorgi, Seyed Mohammad Hosseininejad, Hamed Amini Ahidashti

Abstract read
In one paragraph

Article in Emergency (Tehran, Iran), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iraj GolikhatirEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Seyed Hossein MontazerEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Nabiollah BagheriEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Fatemeh JahanianEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Farzad BozorgiEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Seyed Mohammad HosseininejadEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Hamed Amini AhidashtiEmergency Department, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBased on the existing studies, measuring serum level of immunoglobulin for making decisions regarding prescription of tetanus prophylaxis seems logical and cost effective. Therefore, the present study was done with the aim of evaluating the diagnostic accuracy of tetanus quick stick (TQS) in comparison with ELISA method in this regard.

methodsThe present diagnostic accuracy study was carried out on trauma patients presenting to emergency department, who were in need of receiving tetanus prophylaxis due to dirty wounds or injuries. Patients' blood was evaluated regarding presence of anti-tetanus antibody via TQS and ELISA methods and screening performance characteristics of TQS in identifying the cases in need of receiving prophylaxis was calculated compared to ELISA as the reference test.

results148 patients with the mean age of 34.58 ± 15.86 years (4-86) were studied (87.8% male). Agreement rate between the results of TQS and ELISA was 0.78 based on calculation of kappa coefficient. Sensitivity, specificity and area under the ROC curve of TQS were estimated to be 100 (95% CI: 96.50 - 100), 66.66 (95% CI: 38.68 - 86.01), and 0.83 (95% CI: 0.68 - 0.98), respectively. If TQS was used, the cost of treatment regarding use of tetabulin could have a 91.7% reduction.

conclusionBased on the findings of the present study, TQS has good diagnostic accuracy in comparison with ELISA and considering its 100% sensitivity and negative predictive value in cases with dirty wound, it can be considered as a reliable tool for screening patients that do not need to receive anti-tetanus prophylaxis.

Indexed as

emergency serviceenzyme-linked immunosorbent assayhospitalimmunoglobulinspoint-of-care testingprevention and controlTetanuswounds and injuries

Identifiers

PMID28894781
PMCPMC5585836

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