Evidence map›Paper›PMID 28894740›Full record

ArticleMatters2017

Increased whole cerebellar serotonin in aged C57BL/6 mice.

Nicholas W DeKorver, Dustin Lichty, Marieke van der Hart, Arash Rassoulpour, Stephen J Bonasera

Abstract read
In one paragraph

Article in Matters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicholas W DeKorverInternal Medicine, University of Nebraska Medical Center; Microdialysis, Brains Online.
Dustin LichtyInternal Medicine, University of Nebraska Medical Center; Microdialysis, Brains Online.
Marieke van der HartInternal Medicine, University of Nebraska Medical Center; Microdialysis, Brains Online.
Arash RassoulpourInternal Medicine, University of Nebraska Medical Center; Microdialysis, Brains Online.
Stephen J BonaseraInternal Medicine, University of Nebraska Medical Center; Microdialysis, Brains Online.
University of Nebraska Medical Center · US

Funding

Modifying age-related changes in mouse neuroinflammation & functional behaviorsR01AG031158 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BONASERA, STEPHEN J · 2009 to 2013
$2.9M
NIA NIH HHS R01 AG031158
6 · The paper itself

Abstract

Mobility and locomotor impairments have high prevalence, morbidity, and significant mortality in older adult populations. Cerebellar functional changes have been implicated in the pathogenesis of these age-related mobility and gait deficits unrelated to stroke, Parkinson's disease, or degenerative joint disease. We thus examined total cerebellar glutamate, glutamine, GABA, glycine, dopamine, norepinephrine, tryptophan, serotonin, alanine, threonine, and asparagine content from male 2-3-month (young,

Indexed as

AgingCerebellumMouseSerotonin

Identifiers

PMID28894740
PMCPMC5591457
OpenAlexW2596695420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.