ReviewMediterranean journal of hematology and infectious diseases2017
Solitary Plasmacytoma.
Review in Mediterranean journal of hematology and infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 71 citations in OpenAlex.
- A new prediction model for overall survival of elderly patients with solitary bone plasmacytoma: A population-based study.Frontiers in public health · 2022Trial
- Ocular adnexal plasmacytoma presenting as a lesion of the plica semilunaris and caruncle in a 21-year-old male.American journal of ophthalmology case reports · 2026Article
- Penile Plasmacytoma: A Rare CaseTurkish journal of haematology : official journal of Turkish Society of Haematology · 2026Article
- A solitary lytic rib lesion mimicking primary Chest Wall malignancy as the initial presentation of multiple myeloma.Oxford medical case reports · 2026Article
- Tracheal Extramedullary Plasmacytoma Causing Near-Complete Airway Obstruction in an HIV-Positive Man: A Case Report and Brief Literature Review.Clinical case reports · 2026Article
- Temporal bone plasmacytoma: An exceptional localization of solitary bone plasmacytoma highlighting the role of multimodal imaging and multidisciplinary management.Radiology case reports · 2026Article
- Solitary plasmacytoma of the tibia: literature review and case report.Frontiers in oncology · 2026Article
- Recurrence of solitary extramedullary plasmacytoma affecting both optic nerves: a case report.American journal of ophthalmology case reports · 2025Article
- Sternal Tumor Resection and Complex Chest Wall Reconstruction of a Solitary Plasmacytoma: A Report of a Rare Case.Cureus · 2025Article
- Solitary Plasmacytomas: Current Status in 2025.Hematology reports · 2025Review
- Presentation of extramedullary myeloma manifestations on B-mode (B-US) and contrast-enhanced ultrasound (CEUS).Journal of ultrasonography · 2025Article
- Preoperative embolization of a solitary bone plasmacytoma of the proximal humerus.Radiology case reports · 2024Article
- Extraosseous Plasmacytomas: A Radiologist's Perspective-A Narrative Review of the Literature.Diagnostics (Basel, Switzerland) · 2024Review
- De Novo Plasmacytoma at the Site of Previous Anterior Cervical Fusion.Neurosurgery practice · 2024Article
- An overview of multiple myeloma: A monoclonal plasma cell malignancy's diagnosis, management, and treatment modalities.Saudi journal of biological sciences · 2024Review
- Successful Treatment of Extraosseous Plasmacytoma of the Oropharynx with Cervical Lymph Node Involvement.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Multiple myeloma in a young female presenting as an aggressive skull-base tumour.SA journal of radiology · 2024Article
- Solitary Bone Plasmacytoma Mimicking Oral Cavity Neoplasm - A Rare Case.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- A Case Report of Plasmacytoma in a 28-Year-Old Patient: Bridging the Age Gap in a Rare Presentation.Cureus · 2023Article
- Multiple Myeloma (Part 1) - Update on Epidemiology, Diagnostic Criteria, Systemic Treatment and Prognosis.Revista brasileira de ortopedia · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solitary plasmacytoma is a rare disease characterized by a localized proliferation of neoplastic monoclonal plasma cells, without evidence of systemic disease. It can be subdivided into solitary bone plasmacytoma if the lesion originates in bone, or solitary extramedullary plasmacytoma if the lesion involves a soft tissue. The incidence of solitary bone plasmacytoma is higher than solitary extramedullary plasmacytoma. Also, the prognosis is different: even if both forms respond well to treatment, overall survival and progression-free survival of solitary bone plasmacytoma are poorer than solitary extramedullary plasmacytoma due to its higher rate of evolution in multiple myeloma. However, the recent advances in the diagnosis of multiple myeloma can better refine also the diagnosis of plasmacytoma. Flow cytometry studies and molecular analysis may reveal clonal plasma cells in the bone marrow; magnetic resonance imaging or 18 Fluorodeoxyglucose positron emission tomography could better define osteolytic bone lesions. A more explicit exclusion of possible occult systemic involvement can avoid cases of misdiagnosed multiple myeloma patients, which were previously considered solitary plasmacytoma and less treated, with an unavoidable poor prognosis. Due to the rarity of the disease, there is no uniform consensus about prognostic factors and treatment. Radiotherapy is the treatment of choice; however, some authors debate about the radiotherapy dose and the relationship with the response rate. Moreover, the role of surgery and chemotherapy is still under debate. Nevertheless, we must consider that the majority of studies include a small number of patients and analyze the efficacy of conventional chemotherapy; few cases are reported concerning the efficacy of novel agents.
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