Evidence map›Paper›PMID 28894551›Full record

ArticleElectronic physician2017

Montelukast versus inhaled mometasone for treatment of otitis media with effusion in children: A randomized controlled trial.

Mohammad Bagher Rahmati, Fatemeh Safdarian, Babak Shiroui, Shahram Zare, Naser Sadeghi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Electronic physician, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02541760 (Monteleukast Versus Inhaled Mometasone for Treatment of Otitis Media With Effusion in Children), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02541760 phase3completednot on this map

Monteleukast Versus Inhaled Mometasone for Treatment of Otitis Media With Effusion in Children

TypeinterventionalSponsorHormozgan University of Medical SciencesRan2014 to 2015Enrolled143ConditionsOtitis Media With EffiusionArmsMonteleukast, Mometasone
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Topical and oral steroids for otitis media with effusion (OME) in children.The Cochrane database of systematic reviews · 2023
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohammad Bagher RahmatiAssociate Professor of Pediatric Infectious Disease, Clinical Research Development Center of Children Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Fatemeh SafdarianAssistant Professor, Department of Pediatrics, Clinical Research Development Center of Children Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Babak ShirouiPediatrician, Clinical Research Development Center Of Children Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Shahram ZarePh.D. of Statistics, Professor, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Naser SadeghiM.D. of Otolaryngology, Assistant Professor, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Hormozgan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOtitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with effusion. Some studies have reported the effects of montelukast and mometasone nasal spray in treatment of otitis media with effusion. However, current information is inadequate in this issue.

objectiveTo compare the effectiveness of montelukast and mometasone nasal spray in treatment of otitis media with effusion in children attending Koodakan hospital in Bandar Abbas, Iran.

methodsThis randomized controlled trial was done on 2- to 6-year-old children attending Koodakan Hospital in Bandar Abbas, southern Iran, in 2014. Patients were divided into three groups of montelukast, mometasone, and control group. Audiometry was done for all patients at baseline and four weeks after treatment. Patients were compared for treatment results. Data were analyzed using SPSS 21.0 software.

resultsA total of 143 children were included in the study. Mean age of the participants were 44.64 ± 18.03 months. There was no significant difference in treatment results in different treatment groups (p>0.05).

conclusionMometasone and montelukast are not effective and not recommended in treatment of otitis media with effusion in children. More studies are needed in this regard.

trial registrationThis study is registered at ClinicalTrials.gov with ClinicalTrials.gov Identifier: NCT02541760.

fundingThe authors received financial support for this research from Hormozgan University of Medical Sciences.

Indexed as

EffusionMometasoneMontelukastOtitis media

Identifiers

PMID28894551
PMCPMC5587009
OpenAlexW2747925542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.