Evidence map›Paper›PMID 28894458›Full record

ReviewFrontiers in genetics2017

The Atg8 Family of Proteins-Modulating Shape and Functionality of Autophagic Membranes.

Iman Abdollahzadeh, Melanie Schwarten, Thomas Gensch, Dieter Willbold, Oliver H Weiergräber

Abstract readReview
In one paragraph

Review in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Emerging mechanisms of ATG8-independent non-canonical autophagy.Journal of physiology and biochemistry · 2026
    Review
  2. Amoebicidal effect of pyocyanin and its mechanism of action againstCurrent research in parasitology & vector-borne diseases · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Quantitative Models of Lipid Transfer and Membrane Contact Formation.Contact (Thousand Oaks (Ventura County, Calif.)) · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. The interplay of autophagy and enterovirus.Seminars in cell & developmental biology · 2020
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Iman AbdollahzadehInstitute of Complex Systems, Structural Biochemistry (ICS-6), Forschungszentrum JülichJülich, Germany.
Melanie SchwartenInstitute of Complex Systems, Structural Biochemistry (ICS-6), Forschungszentrum JülichJülich, Germany.
Thomas GenschInstitute of Complex Systems, Cellular Biophysics (ICS-4), Forschungszentrum JülichJülich, Germany.
Dieter WillboldInstitute of Complex Systems, Structural Biochemistry (ICS-6), Forschungszentrum JülichJülich, Germany.
Oliver H WeiergräberInstitute of Complex Systems, Structural Biochemistry (ICS-6), Forschungszentrum JülichJülich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is a multifactorial process involving an accumulation of alterations on various organizational levels, which finally compromises viability and limits the lifespan of organisms. It is now well-established that many aspects of aging can be positively affected by (macro)autophagy, a mechanism of self-digestion found in virtually all eukaryotic cells. A comprehensive understanding of autophagy is thus expected to not only deepen our insight into the mechanisms of aging but to also open up new avenues toward increasing the healthy lifespan in humans. In this review, we focus on the Atg8 family of ubiquitin-like proteins, which play a crucial role in the autophagy process by virtue of their unique mode of reversible membrane association.

Indexed as

agingautophagylipidationmembrane curvaturemembrane fusion

Identifiers

PMID28894458
PMCPMC5581321

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.