Evidence map›Paper›PMID 28894125›Full record

ArticleScientific reports2017

Elongation factor Tu is a multifunctional and processed moonlighting protein.

Michael Widjaja, Kate Louise Harvey, Lisa Hagemann, Iain James Berry, Veronica Maria Jarocki, Benjamin Bernard Armando Raymond, Jessica Leigh Tacchi, Anne Gründel, Joel Ricky Steele, Matthew Paul Padula and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 131 citations in OpenAlex.

  1. Article
  2. Secretome Profiling ofAntibiotics (Basel, Switzerland) · 2026
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  3. The antivirulence effect of 5-iodoindole onCurrent research in microbial sciences · 2026
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  4. D81 Mutants Reveal Hidden EF-Tu Diversity while Natural Sequences Preserve Aspartate.Computational and structural biotechnology journal · 2026
    Article
  5. Strain-Specific Safety Evaluation ofFood science & nutrition · 2025
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  12. Updated Methods for Elucidating Bacterial Surfaceomes.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Molecular Identification and Bioinformatics Analysis ofPathogens (Basel, Switzerland) · 2024
    Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Michael WidjajaThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.
Kate Louise HarveyThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.
Lisa HagemannTechnische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Institut für Medizinische Mikrobiologie und Hygiene, Fetscherstrasse 74, 01307, Dresden, Germany.
Iain James BerryThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.ORCID 0000-0002-0322-2595
Veronica Maria JarockiThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.
Benjamin Bernard Armando RaymondThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.
Jessica Leigh TacchiThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.
Anne GründelTechnische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Institut für Medizinische Mikrobiologie und Hygiene, Fetscherstrasse 74, 01307, Dresden, Germany.
Joel Ricky SteeleThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.ORCID 0000-0002-3070-9761
Matthew Paul PadulaProteomics Core Facility, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia.
Ian George CharlesQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk, NR4 7UA, UK.
Roger DumkeTechnische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Institut für Medizinische Mikrobiologie und Hygiene, Fetscherstrasse 74, 01307, Dresden, Germany.
Steven Philip DjordjevicThe ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia. Steven.Djordjevic@uts.edu.au.
University of Technology Sydney · AUCarl Gustav Carus-Institut · DENorwich Research Park · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many bacterial moonlighting proteins were originally described in medically, agriculturally, and commercially important members of the low G + C Firmicutes. We show Elongation factor Tu (Ef-Tu) moonlights on the surface of the human pathogens Staphylococcus aureus (Sa

Indexed as

Computational BiologyFibrinolysinHost-Pathogen InteractionsMembrane ProteinsModels, MolecularMycoplasma hyopneumoniaeMycoplasma pneumoniaePeptide Elongation Factor TuPlasminogenProtein BindingStaphylococcus aureusVirulence FactorsFibrinolysinMembrane ProteinsPeptide Elongation Factor TuPlasminogenVirulence Factors

Identifiers

PMID28894125
PMCPMC5593925
OpenAlexW2750987002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.