Evidence map›Paper›PMID 28893988›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Cryo-EM structure of the bacteriophage T4 isometric head at 3.3-Å resolution and its relevance to the assembly of icosahedral viruses.

Zhenguo Chen, Lei Sun, Zhihong Zhang, Andrei Fokine, Victor Padilla-Sanchez, Dorit Hanein, Wen Jiang, Michael G Rossmann, Venigalla B Rao

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Review
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  12. Journal of virology · 2025
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  16. Structure ofViruses · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhenguo ChenDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907.
Lei SunDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907.
Zhihong ZhangDepartment of Biology, The Catholic University of America, Washington, DC 20064.
Andrei FokineDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907.
Victor Padilla-SanchezDepartment of Biology, The Catholic University of America, Washington, DC 20064.
Dorit HaneinBioinformatics and Structural Biology Program, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037.
Wen JiangDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907.
Michael G RossmannDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907; mr@purdue.edu rao@cua.edu.
Venigalla B RaoDepartment of Biology, The Catholic University of America, Washington, DC 20064; mr@purdue.edu rao@cua.edu.

Funding

Ultrastructural Basis of Mechanotransduction in Matrix AdhesionsP01GM098412 · NIGMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI GROISMAN, ALEX · 2011 to 2015
$8.0M
Structural studies of bacteriophage T4 and their potential medical applicationsR01AI081726 · NIAID · PURDUE UNIVERSITY · PI KUHN, RICHARD J., RAO, VENIGALLA B. · 2010 to 2019
$6.2M
Phase T4 Head Assembly and Initiation of InfectionR01AI011676 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BLACK, LINDSAY W · 1985 to 2013
$4.1M
STRUCTURE OF A SMALL SPHERICAL VIRUSR01AI011219 · NIAID · PURDUE UNIVERSITY WEST LAFAYETTE · PI KUHN, RICHARD J. · 1985 to 2020
$2.4M
Instrumentation Upgrade: acquisition of an intermediate voltage TEMS10OD012372 · OD · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI HANEIN, DORIT · 2012 to 2012
$1.9M
Structural studies of bacteriophage T4 and their potential medical applicationsR56AI081726 · NIAID · PURDUE UNIVERSITY · PI ROSSMANN, MICHAEL G · 2009 to 2009
$600k
NIAID NIH HHS R01 AI011219NIAID NIH HHS R01 AI011676NIAID NIH HHS R01 AI081726NIAID NIH HHS R56 AI081726NIGMS NIH HHS P01 GM098412NIH HHS S10 OD012372
6 · The paper itself

Abstract

The 3.3-Å cryo-EM structure of the 860-Å-diameter isometric mutant bacteriophage T4 capsid has been determined. WT T4 has a prolate capsid characterized by triangulation numbers (T numbers) T

Indexed as

Bacteriophage T4CapsidCapsid ProteinsCryoelectron MicroscopyCrystallography, X-RayModels, MolecularMutationProtein Structure, SecondaryVirionVirus AssemblyCapsid Proteinsgene 24 protein, Enterobacteria phage T4gp23 protein, Bacteriophage T4bacteriophage T4capsid decoration proteinsisometric headtriangulation numbersvirus capsid assembly

Identifiers

PMID28893988
PMCPMC5625921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.