Evidence map›Paper›PMID 28893949›Full record

ArticleDevelopment (Cambridge, England)2017

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

Yewei Xing, Ken-Ichirou Morohashi, Holly A Ingraham, Gary D Hammer

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Adrenocortical stem cells in health and disease.Nature reviews. Endocrinology · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Development and function of the fetal adrenal.Reviews in endocrine & metabolic disorders · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Adrenal cortex renewal in health and disease.Nature reviews. Endocrinology · 2021
    Review
  12. Article
  13. Review
  14. The role of SUMOylation during development.Biochemical Society transactions · 2020
    Review
  15. Review
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yewei XingDepartment of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan Health System, Ann Arbor, MI 48109-2200, USA.
Ken-Ichirou MorohashiDepartment of Molecular Biology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.
Holly A IngrahamDepartment of Cellular Molecular Pharmacology, School of Medicine, University of California, San Francisco, CA 94158, USA.
Gary D HammerDepartment of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan Health System, Ann Arbor, MI 48109-2200, USA ghammer@umich.edu.ORCID 0000-0001-6843-3628
Michigan Medicine · USKyushu University · JPUniversity of California, San Francisco · US

Funding

Mechanisms of Adrenal DifferentiationR01DK062027 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARY D. HAMMER · 2004 to 2026
$8.0M
Mapping Hypothalamic Neurocircuits Controlling Physical ActivityR01DK099722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI INGRAHAM, HOLLY A. · 2014 to 2018
$2.0M
NIDDK NIH HHS R01 DK062027NIDDK NIH HHS R01 DK099722
6 · The paper itself

Abstract

The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1, Ad4bp) is crucial for formation, development and function of steroidogenic tissues. A fetal adrenal enhancer (FAdE) in the

Indexed as

Gene Expression Regulation, DevelopmentalAdrenal CortexAnimalsDAX-1 Orphan Nuclear ReceptorFemaleHEK293 CellsHumansMaleMiceMice, Inbred C57BLMice, KnockoutProtein Processing, Post-TranslationalReal-Time Polymerase Chain ReactionSteroidogenic Factor 1SumoylationTranscription, GeneticDAX-1 Orphan Nuclear ReceptorNr0b1 protein, mouseSteroidogenic Factor 1steroidogenic factor 1, mouseAdrenal glandNuclear receptorsSUMOylationX-zone

Identifiers

PMID28893949
PMCPMC5675444
OpenAlexW2753786506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.