Evidence map›Paper›PMID 28893948›Full record

ArticleDevelopment (Cambridge, England)2017

Epithelial-mesenchymal transition transcription factors control pluripotent adult stem cell migration

Prasad Abnave, Ellen Aboukhatwa, Nobuyoshi Kosaka, James Thompson, Mark A Hill, A Aziz Aboobaker

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. eLife · 2026
    Article
  3. Extracellular matrix remodeling supportsbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. bioRxiv : the preprint server for biology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. A Planarian Model System to Study Host-Pathogen Interactions.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  14. Live Immunostaining and Flow Cytometry of Schmidtea Mediterranea Cells.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prasad AbnaveDepartment of Zoology, Tinbergen Building, South Parks Road, University of Oxford, Oxford OX1 3PS, UK.
Ellen AboukhatwaDepartment of Zoology, Tinbergen Building, South Parks Road, University of Oxford, Oxford OX1 3PS, UK.
Nobuyoshi KosakaDepartment of Zoology, Tinbergen Building, South Parks Road, University of Oxford, Oxford OX1 3PS, UK.
James ThompsonCRUK/MRC Oxford Institute for Radiation Oncology, ORCRB Roosevelt Drive, University of Oxford, Oxford OX3 7DQ, UK.
Mark A HillCRUK/MRC Oxford Institute for Radiation Oncology, ORCRB Roosevelt Drive, University of Oxford, Oxford OX3 7DQ, UK.
A Aziz AboobakerDepartment of Zoology, Tinbergen Building, South Parks Road, University of Oxford, Oxford OX1 3PS, UK Aziz.Aboobaker@zoo.ox.ac.uk.ORCID 0000-0003-4902-5797
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research CouncilCancer Research UKMedical Research Council MC_U142760473Medical Research Council MR/M000133/1
6 · The paper itself

Abstract

Migration of stem cells underpins the physiology of metazoan animals. For tissues to be maintained, stem cells and their progeny must migrate and differentiate in the correct positions. This need is even more acute after tissue damage by wounding or pathogenic infection. Inappropriate migration also underpins metastasis. Despite this, few mechanistic studies address stem cell migration during repair or homeostasis in adult tissues. Here, we present a shielded X-ray irradiation assay that allows us to follow stem cell migration in planarians. We demonstrate the use of this system to study the molecular control of stem cell migration and show that

Indexed as

Cell MovementEpithelial-Mesenchymal TransitionAdult Stem CellsAnimalsCell LineageCell ShapeConserved SequenceEpidermal CellsIntegrin beta ChainsMatrix MetalloproteinasesPlanariansPluripotent Stem CellsSnail Family Transcription FactorsTranscription FactorsX-RaysIntegrin beta ChainsMatrix MetalloproteinasesSnail Family Transcription FactorsTranscription FactorsEMTMigrationPlanarianPluripotencySchmidtea mediterraneaSnailWounding

Identifiers

PMID28893948
PMCPMC5665486
OpenAlexW2753977491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.