ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Distinct Patterns of Temporal and Directional Connectivity among Intrinsic Networks in the Human Brain.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Methodologies to detect cortico-cortical evoked potentials: a systematic review.Frontiers in human neuroscience · 2025Pooled it
- Targeting intracranial electrical stimulation to network regions defined within individuals causes network-level effects.Journal of neurophysiology · 2026Article
- Cortico-cortical evoked potentials: Analytical techniques and emerging paradigms for epileptogenic zone localization.Epilepsia · 2025Review
- Motor and default mode network states of rest in frontal lobe epilepsy.Neuroimage. Reports · 2025Article
- Thalamus, evoked responses and triphasic waves.Nature communications · 2025Article
- Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks.Nature communications · 2025Article
- Cross-regional coordination of activity in the human brain during autobiographical self-referential processing.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Electrical Stimulation of Temporal and Limbic Circuitry Produces Distinct Responses in Human Ventral Temporal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Temperament & Character account for brain functional connectivity at rest: A diathesis-stress model of functional dysregulation in psychosis.Molecular psychiatry · 2023Review
- Network-specific metabolic and haemodynamic effects elicited by non-invasive brain stimulation.Nature. Mental health · 2023Article
- Review
- Causal mapping of human brain function.Nature reviews. Neuroscience · 2022Review
- Temporal order of signal propagation within and across intrinsic brain networks.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Altered sense of self during seizures in the posteromedial cortex.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Novel Asleep Techniques for Intraoperative Assessment of Brain Connectivity.Frontiers in neurology · 2021Article
- Intrinsic network architecture predicts the effects elicited by intracranial electrical stimulation of the human brain.Nature human behaviour · 2020Article
- Default-mode network streams for coupling to language and control systems.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Individualized perturbation of the human connectome reveals reproducible biomarkers of network dynamics relevant to cognition.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- The disengaging brain: Dynamic transitions from cognitive engagement and alcoholism risk.NeuroImage · 2020Article
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
To determine the spatiotemporal relationships among intrinsic networks of the human brain, we recruited seven neurosurgical patients (four males and three females) who were implanted with intracranial depth electrodes. We first identified canonical resting-state networks at the individual subject level using an iterative matching procedure on each subject's resting-state fMRI data. We then introduced single electrical pulses to fMRI pre-identified nodes of the default network (DN), frontoparietal network (FPN), and salience network (SN) while recording evoked responses in other recording sites within the same networks. We found bidirectional signal flow across the three networks, albeit with distinct patterns of evoked responses within different time windows. We used a data-driven clustering approach to show that stimulation of the FPN and SN evoked a rapid (<70 ms) response that was predominantly higher within the SN sites, whereas stimulation of the DN led to sustained responses in later time windows (85-200 ms). Stimulations in the medial temporal lobe components of the DN evoked relatively late effects (>130 ms) in other nodes of the DN, as well as FPN and SN. Our results provide temporal information about the patterns of signal flow between intrinsic networks that provide insights into the spatiotemporal dynamics that are likely to constrain the architecture of the brain networks supporting human cognition and behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.