Evidence map›Paper›PMID 28893869›Full record

ArticleThe European respiratory journal2017

The

Rachel K Putman, Gunnar Gudmundsson, Tetsuro Araki, Mizuki Nishino, Sigurdur Sigurdsson, Elías F Gudmundsson, Gudny Eiríksdottír, Thor Aspelund, James C Ross, Raúl San José Estépar and 16 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The European respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Visual and Quantitative Interstitial Lung Abnormality Progression in COPDGene.American journal of respiratory and critical care medicine · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. International journal of molecular sciences · 2025
    Observational
  13. Review
  14. Article
  15. Article
  16. Article
  17. Approach to Clinical Trials for the Prevention of Pulmonary Fibrosis.Annals of the American Thoracic Society · 2023
    Article
  18. A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.American journal of respiratory and critical care medicine · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 5 institutions in 3 countries.

Rachel K PutmanPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Gunnar GudmundssonDept of Respiratory Medicine and Sleep, Faculty of Medicine, Landspital University Hospital, University of Iceland, Reykjavik, Iceland.
Tetsuro ArakiDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Mizuki NishinoDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Sigurdur SigurdssonIcelandic Heart Association, Kopavogur, Iceland.
Elías F GudmundssonIcelandic Heart Association, Kopavogur, Iceland.
Gudny EiríksdottírIcelandic Heart Association, Kopavogur, Iceland.
Thor AspelundIcelandic Heart Association, Kopavogur, Iceland.ORCID 0000-0002-7998-5433
James C RossThe Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Raúl San José EstéparDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Ezra R MillerPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Yoshitake YamadaDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Masahiro YanagawaDept of Radiology, Osaka University Graduate School of Medicine, Suita-city, Osaka, Japan.
Noriyuki TomiyamaDept of Radiology, Osaka University Graduate School of Medicine, Suita-city, Osaka, Japan.
Lenore J LaunerIntramural Research Program, National Institute of Aging, NIH, Bethesda, MD, USA.
Tamara B HarrisIntramural Research Program, National Institute of Aging, NIH, Bethesda, MD, USA.
Souheil El-ChemalyPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Benjamin A RabyPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Michael H ChoPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Ivan O RosasPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
George R WashkoPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
David A SchwartzDept of Medicine, University of Colorado, Denver, CO, USA.
Edwin K SilvermanPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Vilmundur GudnasonIcelandic Heart Association, Kopavogur, Iceland.
Hiroto HatabuDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Gary M HunninghakePulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA ghunninghake@partners.org.
Brigham and Women's Hospital · USIcelandic Heart Association · ISUniversity of Iceland · ISThe University of Osaka · JPUniversity of Colorado Denver · US

Funding

Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
Therapeutic Control of Aspirin-Exacerbated Respiratory DiseaseU19AI095219 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Nora Amanda Barrett · 2011 to 2026
$29.1M
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9M
Mechanisms of Familial Pulmonary FibrosisP01HL092870 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SCHWARTZ, DAVID ALBERT · 2010 to 2020
$21.6M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)R01HL097163 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI FINGERLIN, TASHA E., SCHWARTZ, DAVID ALBERT · 2009 to 2018
$16.4M
RESPIRATORY RESEARCHT32HL007633 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI George R Washko · 1985 to 2026
$14.9M
Systems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2016 to 2020
$12.6M
Clinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0M
Genetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung AbnormalitiesR01HL135142 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL H. CHO, GARY MATTHEW HUNNINGHAKE · 2017 to 2026
$7.7M
The Integrative Genomics of Acute Asthma ControlR01HL118455 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MILLSTEIN, JOSHUA, RABY, BENJAMIN ALEXANDER · 2014 to 2024
$6.5M
BLRD VA I01 BX001534NCI NIH HHS K23 CA157631NHLBI NIH HHS K25 HL104085NHLBI NIH HHS K25 HL130637NHLBI NIH HHS P01 HL092870NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL097163NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL113264NHLBI NIH HHS R01 HL116473NHLBI NIH HHS R01 HL118455NHLBI NIH HHS R01 HL122464NHLBI NIH HHS R01 HL123546NHLBI NIH HHS R01 HL129920NHLBI NIH HHS R01 HL130275NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R33 HL120770NHLBI NIH HHS R33 HL120794NHLBI NIH HHS T32 HL007633NHLBI NIH HHS U01 HL089856NHLBI NIH HHS UH2 HL123442NIAID NIH HHS U19 AI095219NIA NIH HHS HHSN271201200022CNIA NIH HHS N01 AG012100NIEHS NIH HHS R25 ES025476
6 · The paper itself

Abstract

The

Indexed as

Polymorphism, GeneticPromoter Regions, GeneticAgedAged, 80 and overFemaleGenotypeHumansIcelandLogistic ModelsLongitudinal StudiesLung Diseases, InterstitialMaleMucin-5BROC CurveTomography, X-Ray ComputedMUC5B protein, humanMucin-5B

Identifiers

PMID28893869
PMCPMC5687883
OpenAlexW2754180290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.