Evidence map›Paper›PMID 28893787›Full record

ArticleAntimicrobial agents and chemotherapy2017

A Four-Center Retrospective Study of the Efficacy and Toxicity of Low-Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Pneumonia in Patients without HIV Infection.

Makoto Kosaka, Atsuhito Ushiki, Yuichi Ikuyama, Kazuya Hirai, Akemi Matsuo, Tsutomu Hachiya, Masayuki Hanaoka

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Trimethoprim-Sulfamethoxazole (Bactrim) Dose Optimization inInternational journal of environmental research and public health · 2022
    Pooled it
  2. Reassessing the efficacy and safety of trimethoprim-sulfamethoxazole for Pneumocystis jirovecii pneumonia: a retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. SAGE open medical case reports · 2024
    Article
  9. Molecular Analysis of Dihydropteroate Synthase Gene Mutations inInternational journal of molecular sciences · 2023
    Article
  10. Pathogens (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Avicenna journal of medicine · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Low-Dose TMP-SMX in the Treatment ofOpen forum infectious diseases · 2020
    Article
  17. Article
  18. Therapy and Management ofJournal of fungi (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Makoto KosakaFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Atsuhito UshikiFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan atsuhito@shinshu-u.ac.jp.
Yuichi IkuyamaFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Kazuya HiraiDepartment of Respiratory Medicine, Nagano Municipal Hospital, Nagano, Japan.
Akemi MatsuoDepartment of Respiratory Medicine, Shinonoi General Hospital, Nagano, Japan.
Tsutomu HachiyaDepartment of Respiratory Medicine, Suwa Red Cross Hospital, Suwa, Japan.
Masayuki HanaokaFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Shinshu University · JPNagano Municipal Hospital · JPShinonoi General Hospital · JPSuwa Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dose of trimethoprim-sulfamethoxazole (TMP-SMX) for the treatment of

Indexed as

AgedFemaleHumansMalePneumocystis cariniiPneumonia, PneumocystisRetrospective StudiesSurvival RateTrimethoprim, Sulfamethoxazole Drug CombinationTrimethoprim, Sulfamethoxazole Drug Combinationlow dosePneumocystis pneumoniarenal impairmenttrimethoprim-sulfamethoxazole

Identifiers

PMID28893787
PMCPMC5700354
OpenAlexW2755239306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.