Evidence map›Paper›PMID 28893786›Full record

ArticleAntimicrobial agents and chemotherapy2017

Novel Cell-Killing Mechanisms of Hydroxyurea and the Implication toward Combination Therapy for the Treatment of Fungal Infections.

Amanpreet Singh, Ameeta Agarwal, Yong-Jie Xu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Amanpreet SinghDepartment of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA.
Ameeta AgarwalNational Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi, USA.
Yong-Jie XuDepartment of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA yong-jie.xu@wright.edu.
University of Mississippi · USWadsworth Center · USWright State University · US

Funding

Signaling Mechanism of the DNA Replication CheckpointR01GM110132 · NIGMS · WRIGHT STATE UNIVERSITY · PI XU, YONGJIE · 2015 to 2020
$1.3M
NIGMS NIH HHS R01 GM110132
6 · The paper itself

Abstract

We have previously reported that an

Indexed as

AlkaloidsAntifungal AgentsAzolesCandida albicansCandidiasisCoproporphyrinogen OxidaseCytochrome P-450 Enzyme SystemCytokinesisDrug SynergismEnzyme InhibitorsHeterocyclic Compounds, 4 or More RingsHydroxyureaMicrobial Sensitivity TestsNaphthyridinesRibonucleotide ReductasesSaccharomyces cerevisiaeAlkaloidsAntifungal AgentsAzolesCoproporphyrinogen OxidaseCytochrome P-450 Enzyme SystemEnzyme InhibitorsErg11 protein, S cerevisiaeHEM13 protein, S cerevisiaeHeterocyclic Compounds, 4 or More RingsHydroxyureaNaphthyridinesRibonucleotide ReductasesSaccharomyces cerevisiae Proteinssampangineantifungal agentsazolescombination therapycytokinesis arresthydroxyureaoxidative stresssampangineterbinafine

Identifiers

PMID28893786
PMCPMC5655065
OpenAlexW2754192248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.