Evidence map›Paper›PMID 28893529›Full record

ArticleRevista Argentina de microbiologia

Passive immunity to control Bovine coronavirus diarrhea in a dairy herd in Argentina.

Marina Bok, Martín Alassia, Flavia Frank, Celina G Vega, Andrés Wigdorovitz, Viviana Parreño

Open access · goldAbstract read
In one paragraph

Article in Revista Argentina de microbiologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  14. Bovine Coronavirus and the Associated Diseases.Frontiers in veterinary science · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marina BokInstituto de Virología, CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Los Reseros y Nicolás Repetto S/N, Castelar, 1712 Buenos Aires, Argentina.
Martín AlassiaDepartamento de Producción Lechera, Facultad de Ciencias Agrarias, Universidad Nacional del Litoral, Kreder 2805, 3080 Esperanza, Santa Fe, Argentina.
Flavia FrankAproAgro S.A., Juan V.B. Mitri 55, S2322EGA, Sunchales, Santa Fe, Argentina.
Celina G VegaInstituto de Virología, CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Los Reseros y Nicolás Repetto S/N, Castelar, 1712 Buenos Aires, Argentina.
Andrés WigdorovitzInstituto de Virología, CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Los Reseros y Nicolás Repetto S/N, Castelar, 1712 Buenos Aires, Argentina.
Viviana ParreñoInstituto de Virología, CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Los Reseros y Nicolás Repetto S/N, Castelar, 1712 Buenos Aires, Argentina. Electronic address: parreno.viviana@inta.gob.ar.
National Agricultural Technology Institute · ARCentro Científico Tecnológico - Santa Fe · ARNational University of the Littoral · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine coronavirus (BCoV) is a viral enteric pathogen associated with calf diarrhea worldwide being, in Argentina, mostly detected in dairy husbandry systems. The aim of the present work was to study if maternal IgG1 antibodies (Abs) to BCoV acquired by colostrum intake modulate the development of BCoV infection in calves reared in a dairy farm in Argentina. Thirty Holstein calves were monitored during their first 60 days of age. Animals were classified into two groups depending on their initial BCoV IgG1 Ab titers. The "failure of passive transfer" (FPT) group had significantly lower IgG1 Abs to BCoV than the "acceptable passive transfer" (APT) group of calves (log10 1.98 vs. 3.38 respectively) (p<0.0001). These differences were also observed when the total protein levels in both groups were compared (p=0.0081). Moreover, 71% (5/7) of calves from the FPT group showed IgG1 seroconversion to BCoV compared to 29.4% (5/17) of animals from the APT group. Regarding viral circulation, BCoV was detected in 10% (3/30) of all calves and BCoV IgG1 Ab seroconversion was detected in 42% of the total animals showing that almost half of the calves were infected with BCoV. In conclusion, calves with high titers of specific BCoV IgG1 (≥1024) were mostly protected against viral infection, while animals with low titers of IgG1 (<1024) were mostly infected with BCoV. IgG1 Abs from colostrum origin are critical for prevention of BCoV infection.

Indexed as

Cattle DiseasesCoronavirus, BovineCoronavirus InfectionsAnimalsAntibodies, ViralArgentinaCattleDiarrheaEnzyme-Linked Immunosorbent AssayFecesFemalePregnancyAntibodies, ViralCoronavirusDiarrea neonatal del terneroInmunidad pasivaNeonatal calf diarrheaPassive immunity

Identifiers

PMID28893529
PMCPMC7116951
OpenAlexW2763774258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.