ArticleeLife2017
Localization of spontaneous bursting neuronal activity in the preterm human brain with simultaneous EEG-fMRI.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Quantifying Cortical Maturational Aspects During Different Vigilance States in Preterm Infants by Advanced EEG Analysis.Journal of sleep research · 2026Article
- Bridging the gap: Translating fetal, infant, and toddler neuroimaging insights into clinical practice.Developmental cognitive neuroscience · 2026Review
- Early life shifts in cortical inhibitory-excitatory balance underlies sensitive periods and skill development.Frontiers in cellular neuroscience · 2026Article
- MeCP2 regulates telencephalic development in human cerebral organoids.Cell reports · 2025Article
- Different Patterns of Cortical Electrical Activity by Tactile, Acoustic and Visual Stimuli in Infants: An EEG Exploratory Study.Diagnostics (Basel, Switzerland) · 2025Article
- Transcriptomic divergence of network hubs in the prenatal human brain.Communications biology · 2025Article
- Impact of touch interventions on brain activity in moderately preterm infants: study protocol for a pilot randomised controlled trial.BMJ open · 2025Article
- Prenatal brain connectivity and postnatal language: how familial risk and prenatal speech exposure shape early language skills.Scientific reports · 2025Article
- Infants' resting-state functional connectivity and event-related potentials: A multimodal approach to investigating the neural basis of infant novelty detection.Developmental psychology · 2025Article
- Understanding the development of a functional brain circuit: reward processing as an illustration.Translational psychiatry · 2025Review
- Whole Brain MRI Assessment of Age and Sex-Related R2* Changes in the Human Fetal Brain.Human brain mapping · 2025Article
- Co-developing sleep-wake and sensory foundations for cognition in the human fetus and newborn.Developmental cognitive neuroscience · 2025Review
- Infant neuroscience: how to measure brain activity in the youngest minds.Trends in neurosciences · 2024Review
- Haemodynamic Responses to Spontaneous Neural Activity on the Electroencephalogram in Preterm Infants.Advances in experimental medicine and biology · 2024Article
- Does Electrophysiological Maturation Shape Language Acquisition?Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- Disrupted resting-sate brain network dynamics in children born extremely preterm.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- An Opportunity to Increase Collaborative Science in Fetal, Infant, and Toddler Neuroimaging.Biological psychiatry · 2023Article
- Parsing brain-behavior heterogeneity in very preterm born children using integrated similarity networks.Translational psychiatry · 2023Article
- Robust sex differences in functional brain connectivity are present in utero.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Atypical Intrinsic Hemispheric Interaction Associated with Autism Spectrum Disorder Is Present within the First Year of Life.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
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7 authors.
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Abstract
Electroencephalographic recordings from the developing human brain are characterized by spontaneous neuronal bursts, the most common of which is the delta brush. Although similar events in animal models are known to occur in areas of immature cortex and drive their development, their origin in humans has not yet been identified. Here, we use simultaneous EEG-fMRI to localise the source of delta brush events in 10 preterm infants aged 32-36 postmenstrual weeks. The most frequent patterns were left and right posterior-temporal delta brushes which were associated in the left hemisphere with ipsilateral BOLD activation in the insula only; and in the right hemisphere in both the insular and temporal cortices. This direct measure of neural and hemodynamic activity shows that the insula, one of the most densely connected hubs in the developing cortex, is a major source of the transient bursting events that are critical for brain maturation.
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