Evidence map›Paper›PMID 28893374›Full record

ArticleeLife2017

Cell differentiation defines acute and chronic infection cell types in

Juan-Carlos García-Betancur, Angel Goñi-Moreno, Thomas Horger, Melanie Schott, Malvika Sharan, Julian Eikmeier, Barbara Wohlmuth, Alma Zernecke, Knut Ohlsen, Christina Kuttler and 1 more

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Article
  3. Regulator-derived growth and fitness costs ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. mBio · 2025
    Article
  6. Article
  7. Strategies for Survival ofInternational journal of molecular sciences · 2025
    Review
  8. Article
  9. Structural characteristics, functions, and counteracting strategies of biofilms inComputational and structural biotechnology journal · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Response ofJournal of bacteriology · 2024
    Article
  14. Article
  15. Article
  16. Current research in microbial sciences · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. An electrogenetic toggle switch model.Microbial biotechnology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juan-Carlos García-BetancurInstitute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.ORCID 0000-0003-3371-3384
Angel Goñi-MorenoSchool of Computing Science, Newcastle University, Newcastle, United Kingdom.
Thomas HorgerDepartment of Mathematics, Technical University of Munich, Garching, Germany.
Melanie SchottInstitute of Clinical Biochemistry and Pathobiochemistry, University Hospital Würzburg, Würzburg, Germany.
Malvika SharanInstitute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Julian EikmeierInstitute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.ORCID 0000-0002-1576-1174
Barbara WohlmuthDepartment of Mathematics, Technical University of Munich, Garching, Germany.
Alma ZerneckeInstitute of Clinical Biochemistry and Pathobiochemistry, University Hospital Würzburg, Würzburg, Germany.
Knut OhlsenInstitute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Christina KuttlerDepartment of Mathematics, Technical University of Munich, Garching, Germany.
Daniel LopezInstitute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.ORCID 0000-0002-8627-3813

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A central question to biology is how pathogenic bacteria initiate acute or chronic infections. Here we describe a genetic program for cell-fate decision in the opportunistic human pathogen

Indexed as

Cell DifferentiationAnimalsBacillus subtilisBacterial ProteinsBase SequenceBiofilmsCell WallDisease Models, AnimalEscherichia coliFemaleFlow CytometryGene Expression Regulation, BacterialGenes, BacterialHeartKidneyMagnesiumAgr protein, Staphylococcus aureusBacterial ProteinsMagnesiumPeptidoglycanRNA, BacterialstaphyloxanthinTeichoic AcidsTrans-ActivatorsXanthophyllscell differentiationinfectious diseasemicrobiologyopportunistic infectionStaphylococcus aureus

Identifiers

PMID28893374
PMCPMC5595439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.