ArticleBMC biology2017
SKIP controls flowering time via the alternative splicing of SEF pre-mRNA in Arabidopsis.
Article in BMC biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- HPlant cell reports · 2026Article
- Splicing Factors in Plant Abiotic Stress Responses: Regulatory Mechanisms and Perspectives.Plants (Basel, Switzerland) · 2026Review
- Intron retention dominates alternative splicing reprogramming during anaerobic stress in Chlamydomonas reinhardtii.Planta · 2026Article
- An F-box protein OsFKF1 interacts with either OsGI or Hd1 and mediates the degradation of OsGI to control flowering time in rice.Science advances · 2026Article
- Transcriptome and weighted gene co-enrichment analysis revealed modules and candidate genes associated with barley response to low potassium stress.Frontiers in plant science · 2026Article
- An auxin response factor regulates tiller angle and shoot gravitropism by directly activating related gene expression in rice.Journal of advanced research · 2025Article
- Regulation of Flowering Time and Other Developmental Plasticities by 3' Splicing Factor-Mediated Alternative Splicing inPlants (Basel, Switzerland) · 2023Review
- Two interacting basic helix-loop-helix transcription factors control flowering time in rice.Plant physiology · 2023Article
- MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control.Development (Cambridge, England) · 2023Article
- Alternative splicing in ABA signaling during seed germination.Frontiers in plant science · 2023Review
- An SNW/SKI-INTERACTING PROTEIN influences endoreduplication and cell growth in Arabidopsis.Plant physiology · 2022Article
- An Arabidopsis Retention and Splicing complex regulates root and embryo development through pre-mRNA splicing.Plant physiology · 2022Article
- A Single Amino Acid Substitution in MIL1 Leads to Activation of Programmed Cell Death and Defense Responses in Rice.International journal of molecular sciences · 2022Article
- Genomic Survey ofPlants (Basel, Switzerland) · 2022Article
- The Importance of a Genome-Wide Association Analysis in the Study of Alternative Splicing Mutations in Plants with a Special Focus on Maize.International journal of molecular sciences · 2022Review
- Nitrilases NIT1/2/3 Positively Regulate Flowering by InhibitingFrontiers in plant science · 2022Article
- Ubiquitination and Ubiquitin-Like Modifications as Mediators of Alternative Pre-mRNA Splicing inFrontiers in plant science · 2022Review
- The SR Splicing Factors: Providing Perspectives on Their Evolution, Expression, Alternative Splicing, and Function inInternational journal of molecular sciences · 2021Article
- The Roles of Temperature-Related Post-Transcriptional Regulation in Cereal Floral Development.Plants (Basel, Switzerland) · 2021Review
- Normal, novel or none: versatile regulation from alternative splicing.Plant signaling & behavior · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSimilar to other eukaryotes, splicing is emerging as an important process affecting development and stress tolerance in plants. Ski-interacting protein (SKIP), a splicing factor, is essential for circadian clock function and abiotic stress tolerance; however, the mechanisms whereby it regulates flowering time are unknown.
resultsIn this study, we found that SKIP is required for the splicing of serrated leaves and early flowering (SEF) pre-messenger RNA (mRNA), which encodes a component of the ATP-dependent SWR1 chromatin remodeling complex (SWR1-C). Defects in the splicing of SEF pre-mRNA reduced H2A.Z enrichment at FLC, MAF4, and MAF5, suppressed the expression of these genes, and produced an early flowering phenotype in skip-1 plants.
conclusionsOur findings indicate that SKIP regulates SWR1-C function via alternative splicing to control the floral transition in Arabidopsis thaliana.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.