ArticleBMC complementary and alternative medicine2017
Assessment of free radical scavenging and anti-proliferative activities of Tinospora cordifolia Miers (Willd).
Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 58 citations in OpenAlex.
- Effects of Tinospora cordifolia (giloy) on metabolic syndrome components: a mechanistic review.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Cytotoxic and immunomodulatory properties of Tinospora cordifolia, Boerhaavia diffusa, Berberis aristata, and Ocimum basilicum extracts against HPV-positive cervical cancer cell line.BMC complementary medicine and therapies · 2025Article
- Antioxidant Potential of Medicinal Plants in the Treatment of Scabies Infestation.Molecules (Basel, Switzerland) · 2024Review
- Cardioprotective Role ofCardiovascular & hematological agents in medicinal chemistry · 2024Article
- Modulating effects of the synergistic combination of extracts of herbal drugs on cyclophosphamide-induced immunosuppressed mice.Saudi journal of biological sciences · 2021Article
- Cordifolioside: potent inhibitor against M3 Biotech · 2021Article
- Sensory acceptability of value added cookies incorporated withJournal of food science and technology · 2020Article
- Antimycobacterial Activity and Safety Profile Assessment ofEvidence-based complementary and alternative medicine : eCAM · 2018Article
- Indian Ayurvedic medicine: Overview and application to brain cancer.Journal of Ayurveda and integrative medicineReview
- Immunomodulatory effect of a proprietary polyherbal formulation on healthy participants: A single- blind, randomized, placebo- controlled, exploratory clinical study.Perspectives in clinical researchArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTinospora cordifolia (Guduchi or Amrita) is an important drug of Ayurvedic System of Medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes, cancer and skin disease etc. In view of its traditional claims, antioxidant and anti-proliferative activities were evaluated in the present study.
methodsEthanol extract (TCE) and subsequent petroleum ether (TCP), dichloromethane (TCD), n-Butanol (TCB) and aqueous (TCA) fractions of were prepared from stems of T cordifolia. Total phenolic, flavonoid content and anti-oxidant activity was assessed by different methods. Anti-proliferative activity was assessed in cervical carcinoma (HeLa) cell lines by MTT and SRB assay.
resultsEthanol extract and n-butanol fractions shown to be superior in their scavenging activity in all the tested methods. n-butanol fractions shown antioxidant activity with an IC
conclusionThe outcomes of the present study support the fact that T Cordifolia is a promising source of antioxidant agent and propose its further investigation. Moreover, dichloromethane fraction of T cordifolia shown to be the most potent anti-proliferative fraction and further mechanistic and phytochemical investigations are under way to identify the active principles.
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