ArticleBMC women's health2017
Effect of periodontitis on the development of osteoporosis: results from a nationwide population-based cohort study (2003-2013).
Article in BMC women's health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Associations between osteoporosis and risk of periodontitis: A pooled analysis of observational studies.Oral diseases · 2021Pooled it
- Influence of symptomatic periodontal disease on changes in skeletal bone density during medication therapy for osteoporosis in postmenopausal women: the Japanese Osteoporosis Intervention Trial (JOINT)-04 and JOINT-05.Archives of osteoporosis · 2021Trial
- Periodontal Disease and Osteoporosis: A Bidirectional Relationship.Advances in experimental medicine and biology · 2026Review
- The oral - X axis: from periodontal dysbiosis to systemic disease.Frontiers in immunology · 2026Review
- Low bone density and periodontal disease in postmenopausal women: A systematic review and meta-analysis.Journal of family medicine and primary care · 2025Review
- Construction of Chitosan Oligosaccharide-Coated Nanostructured Lipid Carriers for the Sustained Release of Strontium Ranelate.Tissue engineering and regenerative medicine · 2025Article
- Article
- Convolutional-neural-network-based radiographs evaluation assisting in early diagnosis of the periodontal bone loss via periapical radiograph.Journal of dental sciences · 2024Article
- General and local predictors of mandibular cortical bone morphology in adult females and males: the seventh survey of the Tromsø Study.Clinical oral investigations · 2023Article
- Periodontal Health and Disease in the Context of Systemic Diseases.Mediators of inflammation · 2023Review
- A Population-Based Study on the Association between Periodontal Disease and Major Lifestyle-Related Comorbidities in South Korea: An Elderly Cohort Study from 2002-2015.Medicina (Kaunas, Lithuania) · 2020Article
- Severe periodontitis with tooth loss as a modifiable risk factor for the development of Alzheimer, vascular, and mixed dementia: National Health Insurance Service-National Health Screening Retrospective Cohort 2002-2015.Journal of periodontal & implant science · 2020Article
- Effect of Periodontal Pathogens on Total Bone Volume Fraction: A Phenotypic Study.Current medical science · 2020Article
- Chronic Periodontal Disease increases risk for Prostate Cancer in Elderly individuals in South Korea: a Retrospective Nationwide Population-based Cohort Study.Journal of Cancer · 2020Article
- Association between oral health and dementia in the elderly: a population-based study in Korea.Scientific reports · 2019Article
- Association between health status and tooth loss in Korean adults: longitudinal results from the National Health Insurance Service-Health Examinee Cohort, 2002-2015.Journal of periodontal & implant science · 2019Article
- Diagnosis and prediction of periodontally compromised teeth using a deep learning-based convolutional neural network algorithm.Journal of periodontal & implant science · 2018Article
- Charlson comorbidity index as a predictor of periodontal disease in elderly participants.Journal of periodontal & implant science · 2018Article
- Trends in the incidence of tooth extraction due to periodontal disease: results of a 12-year longitudinal cohort study in South Korea.Journal of periodontal & implant science · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of osteoporosis associated with the aging process is anticipated to increase along with the rising aging population. Periodontitis that the most common chronic infections of humankind is considered the risk factor for osteoporosis. The aim of this study was to identify the association between osteoporosis and periodontitis using a population-based cohort.
methodsThe case group was defined as patients diagnosed with periodontitis and treated with subgingival curettage, root conditioning, periodontal flap operation, bone grafting for alveolar bone defects, and guided tissue regeneration. Case and control groups matched for gender, age, household income, type of social security, disability, and residential area were generated. A Cox proportional hazard model was constructed to examine the difference in the development of osteoporosis between the case and control groups. The final sample included 13,464 participants.
resultsThe incidence of osteoporosis was 1.1% in males and 15.8% in females during a 10-year period. The risk factors for osteoporosis in males were increasing age and Charlson Comorbidity Index score. Periodontitis was not associated with the development of osteoporosis in males. The risk factors for osteoporosis in females were increasing age, body mass index, Charlson Comorbidity Index score, diabetes, and periodontitis. Women with periodontitis were more likely to also develop osteoporosis (HR: 1.22, 95% CI: 1.01-1.48).
conclusionsPeriodontitis has an effect on the development of osteoporosis in females. Managing good teeth is required for the prevention and delay of osteoporosis. This includes dental examinations, regular cleanings and gum treatment.
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Registered trials
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