ArticleBMC infectious diseases2017
Hepatitis B virus and HIV co-infection among pregnant women in Rwanda.
Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Vertical transmission of hepatitis B virus in the WHO African region: a systematic review and meta-analysis.The Lancet. Global health · 2025Pooled it
- Epidemiology of hepatitis B virus infection among pregnant women in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- The burden of Hepatitis B virus infection in Kenya: A systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Pooled it
- Seroprevalence of HIV among pregnant women in Ethiopia: a systematic review and meta-analysis.BMC research notes · 2018Pooled it
- Seroepidemiology ofBioMed research international · 2018Trial
- Prevalence and associated factors for HIV, HBV and syphilis coinfections among pregnant women attending antenatal care in Tanzania.PloS one · 2025Article
- Seroprevalence of Hepatitis B and C and HIV Infections and Associated Risk Factors Among Pregnant Women Attending Antenatal Care Unit at Simada Hospital, South Gondar Zone, Northwest Ethiopia.BioMed research international · 2025Article
- Antenatal Screening for Hepatitis B Virus in Uganda: Missed Opportunities for Diagnosis and Treatment.Open forum infectious diseases · 2024Article
- HIV and hepatitis B, C co-infection and correlates of HIV infection among men who have sex with men in Rwanda, 2021: a respondent-driven sampling, cross-sectional study.BMC infectious diseases · 2024Article
- Article
- Antenatal hepatitis B virus sero-prevalence, risk factors, pregnancy outcomes and vertical transmission rate within 24 months after birth in a high HIV prevalence setting.BMC infectious diseases · 2023Article
- Economic analysis of a new four-panel rapid screening test in antenatal care in Kenya, Rwanda, and Uganda.BMC health services research · 2023Article
- Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study.Infectious diseases of poverty · 2023Article
- Seroprevalence and Risk Factors of Sexually Transmitted Blood-Borne Infections among Pregnant Women Attending Antenatal Care in Jirapa, Upper West Region of Ghana.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Article
- Prevalence ofFrontiers in global women's health · 2023Article
- Male partners involvement in human immune deficiency virus testing and counseling during prenatal care visits in Bichena town Westcentral Ethiopia: a cross-sectional study.BMC research notes · 2022Article
- Article
- Prevalence of HIV and hepatitis B virus among pregnant women in Luanda (Angola): geospatial distribution and its association with socio-demographic and clinical-obstetric determinants.Virology journal · 2021Article
- Association between micronutrients and maternal leukocyte telomere length in early pregnancy in Rwanda.BMC pregnancy and childbirth · 2020Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundHepatitis B virus (HBV) affects people worldwide but the local burden especially in pregnant women and their new born babies is unknown. In Rwanda HIV-infected individuals who are also infected with HBV are supposed to be initiated on ART immediately. HBV is easily transmitted from mother to child during delivery. We sought to estimate the prevalence of chronic HBV infection among pregnant women attending ante-natal clinic (ANC) in Rwanda and to determine factors associated with HBV and HIV co-infection.
methodsThis study used a cross-sectional survey, targeting pregnant women in sentinel sites. Pregnant women were tested for hepatitis B surface antigen (HBsAg) and HIV infection. A series of tests were done to ensure high sensitivity. Multivariable logistic regression was used to identify independent predictors of HBV-HIV co-infection among those collected during ANC sentinel surveillance, these included: age, marital status, education level, occupation, residence, pregnancy and syphilis infection.
resultsThe prevalence of HBsAg among 13,121 pregnant women was 3.7% (95% CI: 3.4-4.0%) and was similar among different socio-demographic characteristics that were assessed. The proportion of HIV-infection among HBsAg-positive pregnant women was 4.1% [95% CI: 2.5-6.3%]. The prevalence of HBV-HIV co-infection was higher among women aged 15-24 years compared to those women aged 25-49 years [aOR = 6.9 (95% CI: 1.8-27.0)]. Women residing in urban areas seemed having HBV-HIV co-infection compared with women residing in rural areas [aOR = 4.3 (95% CI: 1.2-16.4)]. Women with more than two pregnancies were potentially having the co-infection compared to those with two or less (aOR = 6.9 (95% CI: 1.7-27.8). Women with RPR-positive test were seemed associated with HBV-HIV co-infection (aOR = 24.9 (95% CI: 5.0-122.9).
conclusionChronic HBV infection is a public health problem among pregnant women in Rwanda. Understanding that HBV-HIV co-infection may be more prominent in younger women from urban residences will help inform and strengthen HBV prevention and treatment programmes among HIV-infected pregnant women, which is crucial to this population.
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