Evidence map›Paper›PMID 28893064›Full record

ArticleBiomacromolecules2017

Aqueous RAFT Synthesis of Glycopolymers for Determination of Saccharide Structure and Concentration Effects on Amyloid β Aggregation.

Pradipta K Das, Dexter N Dean, April L Fogel, Fei Liu, Brooks A Abel, Charles L McCormick, Eugenia Kharlampieva, Vijayaraghavan Rangachari, Sarah E Morgan

Open access · greenAbstract read
In one paragraph

Article in Biomacromolecules, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Biophysical characteristics of lipid-induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pradipta K Das
April L Fogel
Fei LiuDepartment of Chemistry, University of Alabama Birmingham , Birmingham, Alabama 35294, United States.
Brooks A Abel
Charles L McCormick
Eugenia KharlampievaDepartment of Chemistry, University of Alabama Birmingham , Birmingham, Alabama 35294, United States.ORCID http://orcid.org/0000-0003-0227-0920
University of Alabama at Birmingham · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
TOUGALOO PROTEOMICSP20RR016476 · NCRR · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI SHEARER, GLEN · 2001 to 2011
$30.4M
Determining the Mechanisms Governing Transmissibility Among Amyloid-beta OligomersR15AG046915 · NIA · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MOSS, MELISSA ANN, RANGACHARI, VIJAY · 2015 to 2015
$368k
NCRR NIH HHS P20 RR016476NIA NIH HHS R15 AG046915NIGMS NIH HHS P20 GM103476
6 · The paper itself

Abstract

GM1 ganglioside is known to promote amyloid-β (Aβ) peptide aggregation in Alzheimer's disease. The roles of the individual saccharides and their distribution in this process are not understood. Acrylamide-based glycomonomers with either β-d-glucose or β-d-galactose pendant groups were synthesized to mimic the stereochemistry of saccharides present in GM1 and characterized via

Indexed as

AcrylamideAmyloid beta-PeptidesBenzothiazolesBiomimetic MaterialsGalactoseGlucoseG(M1) GangliosidePolymerizationProtein AggregatesThiazolesAcrylamideAmyloid beta-PeptidesBenzothiazolesGalactoseGlucoseG(M1) GangliosideProtein AggregatesThiazolesthioflavin T

Identifiers

PMID28893064
PMCPMC5694895
OpenAlexW2755454576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.