ReviewCurrent opinion in immunology2017
Immune mechanisms of food allergy and its prevention by early intervention.
Review in Current opinion in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Immunological Mechanisms and Outcomes of T-cell-Targeted Immunotherapy in Food Allergy: A Systematic Review.Clinical reviews in allergy & immunology · 2025Pooled it
- Gut mucosal immune responses - Implications for celiac disease and food allergy.Seminars in immunology · 2025Review
- Golden eyes on pollutants: colorimetric detection of emerging contaminants with AuNPs.RSC advances · 2025Review
- Food Protein-Induced Allergic Proctocolitis: Real-World Experience from an Italian Cohort.Nutrients · 2024Observational
- The Effectiveness of Early Food Introduction in Preventing Childhood Allergic Diseases: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2023Article
- Article
- Advances in the Study of the Mechanism by Which Selenium and Selenoproteins Boost Immunity to Prevent Food Allergies.Nutrients · 2022Review
- The Interplay of Nutriepigenomics, Personalized Nutrition and Clinical Practice in Managing Food Allergy.Life (Basel, Switzerland) · 2021Review
- Mass spectrometric analysis of digesta does not improve the allergenicity assessment of GM crops.Transgenic research · 2021Article
- Early life microbial exposures and allergy risks: opportunities for prevention.Nature reviews. Immunology · 2021Review
- Peanut (The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021Article
- Evidence runs contrary to digestive stability predicting protein allergenicity.Transgenic research · 2020Article
- Role of Vitamin D in Prevention of Food Allergy in Infants.Frontiers in pediatrics · 2020Review
- Indoor dust acts as an adjuvant to promote sensitization to peanut through the airway.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Article
- Microbiota and Food Allergy.Clinical reviews in allergy & immunology · 2019Review
- Prevention of Food Allergy: The Significance of Early Introduction.Medicina (Kaunas, Lithuania) · 2019Review
- Immunomodulatory Protein Hydrolysates and Their Application.Nutrients · 2018Review
- Environmental Food Exposure: What Is the Risk of Clinical Reactivity From Cross-Contact and What Is the Risk of Sensitization.The journal of allergy and clinical immunology. In practiceReview
- Biomarkers in oral immunotherapy.Journal of Zhejiang University. Science. BReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
The environmental factors driving the increase in food allergies are unclear and possibly involve dual exposure to allergens, microbiome-driven effects or other mechanisms. Until they can be better understood, early intervention aiming at establishing oral tolerance provides an effective way to decrease the window-of-risk when children may develop allergic sensitisation to foods due to the absence of a protective immune response. Thus, the recent LEAP (Learning Early About Peanut allergy) and LEAP-On studies achieved a high level of peanut allergy prevention by early introduction of peanuts in the infants diet and conveyed more information regarding the evolution of IgE and IgG4 antibody responses to food antigens over time.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.