Trial reportJournal of dental research2018
Self-assembling Peptide P
Trial report in Journal of dental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Biomimetic Remineralization Using Self-Assembling Peptide P11-4 in the Prevention and Treatment of Early Carious Lesions in Primary Anterior Teeth: An In-Vivo and In-Vitro Study
An Observational Multi-cite Study to Evaluate and Compare the Effectiveness of Various Tooth Specific Treatments in the Management of Early Caries Lesions
Who cites it
59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 113 citations in OpenAlex.
- Self-assembling peptides for managing white spot lesions: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Pooled it
- Comparison of therapies of white spot lesions: a systematic review and network meta-analysis.BMC oral health · 2023Pooled it
- Nonrestorative Caries Treatment: A Systematic Review Update.International dental journal · 2022Pooled it
- Interventions for treating cavitated or dentine carious lesions.The Cochrane database of systematic reviews · 2021Pooled it
- Arginine Dentifrices and Childhood Caries Prevention: A Randomized Clinical Trial.JDR clinical and translational research · 2026Trial
- A prospective, triple-blind, randomized controlled clinical trial evaluating the protective effect of P11-4 peptide on enamel demineralization during multibracket orthodontic treatment.BMC oral health · 2026Trial
- Evaluation of the remineralization potential of self-assembling peptide P11-4 with fluoride compared to fluoride varnish in the management of incipient carious lesions: a randomized controlled clinical trial.Clinical oral investigations · 2024Trial
- Self-assembling peptide and nano-silver fluoride in remineralizing early enamel carious lesions: randomized controlled clinical trial.BMC oral health · 2023Trial
- Evaluation of the remineralizing effect of biomimetic self-assembling peptides in post-orthodontic white spot lesions compared to fluoride-based delivery systems: randomized controlled trial.Clinical oral investigations · 2023Trial
- Effect of the caries-protective self-assembling peptide P11-4 on shear bond strength of metal brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2021Trial
- Efficacy of PScientific reports · 2020Trial
- Impact of self-assembling peptides in remineralisation of artificial early enamel lesions adjacent to orthodontic brackets.Scientific reports · 2020Trial
- Effect of self-assembling peptide PScientific reports · 2020Trial
- Randomized Clinical Trial investigating Self-Assembling Peptide PScientific reports · 2020Trial
- Randomised clinical trial investigating self-assembling peptide PClinical oral investigations · 2020Trial
- Randomised in situ clinical trial investigating self-assembling peptide matrix P11-4 in the prevention of artificial caries lesions.Scientific reports · 2019Trial
- Is there consensus for the treatment of initial to moderate caries lesions? - a Delphi first-round study.BMC oral health · 2026Article
- Comparative evaluation of remineralization agents in severe enamel hypomineralization using a porcine enamel model.BMC oral health · 2026Article
- Remineralization of Initial Carious Lesions Using Peptides: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2026Review
- Comparison of the effect of self-assembling peptide PBMC oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regenerative medicine-based approaches for caries treatment focus on biomimetic remineralization of initial carious lesions as a minimal invasive therapy. In vitro, self-assembling peptide P
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.