Evidence map›Paper›PMID 28892506›Full record

ArticlePloS one2017

Does progestin-only contraceptive use after pregnancy affect recovery from pelvic girdle pain? A prospective population study.

Elisabeth Krefting Bjelland, Katrine Mari Owe, Hedvig Marie Egeland Nordeng, Bo Lars Engdahl, Per Kristiansson, Siri Vangen, Malin Eberhard-Gran

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Elisabeth Krefting BjellandHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.ORCID http://orcid.org/0000-0003-3206-524X
Katrine Mari OweNorwegian National Advisory Unit on Women's Health, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Hedvig Marie Egeland NordengDepartment of Child Health, Norwegian Institute of Public Health, Oslo, Norway.
Bo Lars EngdahlDepartment of Health and Aging, Norwegian Institute of Public Health, Oslo, Norway.
Per KristianssonDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Siri VangenNorwegian National Advisory Unit on Women's Health, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Malin Eberhard-GranHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.
Norwegian Institute of Public Health · NOOslo University Hospital · NOUppsala University · SE

Funding

Gene-Environment Interactions in an Autism Birth CohortU01NS047537 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2003 to 2013
$27.0M
NIEHS NIH HHS N01 ES075558NINDS NIH HHS U01 NS047537
6 · The paper itself

Abstract

objectiveTo estimate associations of progestin-only contraceptives with persistent pelvic girdle pain 18 months after delivery.

methodsProspective population based cohort study during the years 2003-2011. We included 20,493 women enrolled in the Norwegian Mother and Child Cohort Study who reported pelvic girdle pain in pregnancy week 30. Data were obtained by 3 self-administered questionnaires and the exposure was obtained by linkage to the Prescription Database of Norway. The outcome was pelvic girdle pain 18 months after delivery.

resultsPelvic girdle pain 18 months after delivery was reported by 9.7% (957/9830) of women with dispense of a progestin-only contraceptive and by 10.5% (1114/10,663) of women without dispense (adjusted odds ratio 0.93; 95% CI 0.84-1.02). In sub-analyses, long duration of exposure to a progestin intrauterine device or progestin-only oral contraceptives was associated with reduced odds of persistent pelvic girdle pain (Ptrend = 0.021 and Ptrend = 0.005). Conversely, long duration of exposure to progestin injections and/or a progestin implant was associated with modest increased odds of persistent pelvic girdle pain (Ptrend = 0.046). Early timing of progestin-only contraceptive dispense following delivery (≤3 months) was not significantly associated with persistent pelvic girdle pain.

conclusionsOur findings suggest a small beneficial effect of progestin intrauterine devices and progestin-only oral contraceptives on recovery from pelvic girdle pain. We cannot completely rule out an opposing adverse effect of exposure to progestin injections and/or progestin implants. However, the modest increased odds of persistent pelvic girdle pain among these users could be a result of unmeasured confounding.

Indexed as

AdultContraceptive AgentsFemaleHumansIntrauterine DevicesNorwayPelvic Girdle PainPopulation SurveillancePregnancyProgestinsProspective StudiesTreatment OutcomeContraceptive AgentsProgestins

Identifiers

PMID28892506
PMCPMC5593199
OpenAlexW2754457263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.