ArticleNature immunology2017
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection.
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Article in Nature immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.
0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
149 citing papers in PubMed, 222 citations in OpenAlex.
- IL-2-producing TNature immunology · 2026Article
- A tolerogenic function for gut TNature immunology · 2026Article
- A cross-vertebrate single-cell and spatial atlas reveals evolutionary trajectories of gastrointestinal cellular innovation.Cell genomics · 2026Article
- CD137 agonists in mice suppress germinal center responses by increasing the immunosuppressive activity of follicular regulatory T-cells.The EMBO journal · 2026Article
- Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026Review
- Regulation of follicular helper T cell subset differentiation in health and disease.Journal of molecular medicine (Berlin, Germany) · 2026Review
- Article
- TGF-β and IL-2 differentially shape T follicular regulatory cell differentiation and stability in vitro.Cellular & molecular immunology · 2026Article
- IL-6-induced C/EBPα drives follicular regulatory T cell differentiation to regulate humoral immunity in mice.Nature communications · 2026Article
- Bioengineered anti-EpCAM-guided exosome nanocarriers delivering Foxp3 agonist butyrate achieve tissue-specific immunomodulation in autoimmune Sjögren's syndrome.Journal of nanobiotechnology · 2026Article
- Cytokines Associated with Activation of CD4International journal of molecular sciences · 2026Review
- Stability and progressive differentiation of TNature immunology · 2026Article
- Low effectiveness of influenza vaccines vis-à-vis mechanism of protection by vaccines - potential causes and recommendations to improve control of influenza.Frontiers in immunology · 2026Review
- Mechanisms of T cell-mediated antitumor immunity within tertiary lymphoid structures.Frontiers in immunology · 2026Review
- BLIMP-1 and CEACAM1 cooperatively regulate human Treg homeostasis and function to control xenogeneic GVHD.JCI insight · 2025Article
- The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice.Blood · 2025Article
- Transcriptome Sequencing and Differential Analysis of Ovaries Across Diverse States (Follicular and Non-Follicular Phases).Animals : an open access journal from MDPI · 2025Article
- Article
- PD-1 and ICOS are coexpressed in T follicular helper cells but define three stages of maturation of T follicular regulatory cells.Science advances · 2025Article
- ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis.Nature communications · 2025Article
89 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on byT2017
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Authors and funding
11 authors at 1 institution in 1 country.
Davide BottaDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID http://orcid.org/0000-0003-3926-0662
Michael J FullerDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, USA.
Tatiana T Marquez-LagoInformatics Institute, University of Alabama at Birmingham, Alabama, USA.
Holly BachusDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, USA.
John E BradleyDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, USA.
Amy S WeinmannDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Allan J ZajacDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Troy D RandallDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, USA.
Frances E LundDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Beatriz LeónDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
André Ballesteros-TatoDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, USA.ORCID http://orcid.org/0000-0002-4833-593X
University of Alabama at Birmingham · US
Funding
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1MVirus-induced Cell Fate Decisions in Anti-Viral ImmunityU19AI109962 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEE, FRANCES EUN-HYUNG · 2014 to 2018
$11.6MROS Modulation of Innate and Adaptive Immunity in RAP30AR048311 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2001 to 2017
$9.5MMolecular characterization of the role for T-bet and Bcl-6 in immune cell metabolism and differentiationR01AI061061 · NIAID · UNIVERSITY OF WASHINGTON · PI WEINMANN, AMY SUSAN · 2004 to 2025
$7.0MRegulation of T Cell Activity During Chronic InfectionsR01AI049360 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZAJAC, ALLAN J · 2001 to 2019
$4.1MRegulation of T cell responses to allergens and environmental microbesR01AI116584 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2015 to 2024
$4.1MRegulation of T-cell dependent B cell responses to influenzaR01AI110480 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALLESTEROS-TATO, ANDRE · 2015 to 2019
$1.8MCentral and Effector B cells in the LungR01AI097357 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2012 to 2016
$1.8MDeveloping and Improving Institutional Animal ResourcesG20RR022807 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARTNER, SAMUEL CORBIN · 2006 to 2006
$647kRegulation of T Cell Activity During Chronic InfectionsR56AI049360 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZAJAC, ALLAN J · 2014 to 2014
$362kNCRR NIH HHS G20 RR022807NIAID NIH HHS P30 AI027767NIAID NIH HHS R01 AI049360NIAID NIH HHS R01 AI061061NIAID NIH HHS R01 AI097357NIAID NIH HHS R01 AI110480NIAID NIH HHS R01 AI116584NIAID NIH HHS R56 AI049360NIAID NIH HHS U19 AI109962NIAMS NIH HHS P30 AR048311
Abstract
Interleukin 2 (IL-2) promotes Foxp3
Indexed as
AnimalsCell MovementForkhead Transcription FactorsGene Expression ProfilingHost-Pathogen InteractionsInterleukin-2Interleukin-2 Receptor alpha SubunitMice, Inbred C57BLMice, KnockoutMice, TransgenicOrthomyxoviridaeOrthomyxoviridae InfectionsPositive Regulatory Domain I-Binding Factor 1Proto-Oncogene Proteins c-bcl-6T-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryForkhead Transcription FactorsFoxp3 protein, mouseInterleukin-2Interleukin-2 Receptor alpha SubunitPositive Regulatory Domain I-Binding Factor 1Prdm1 protein, mouseProto-Oncogene Proteins c-bcl-6Transcription Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.