Evidence map›Paper›PMID 28892414›Full record

ArticleHuman vaccines & immunotherapeutics2017

Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model.

Qingjie Xue, Xiuzhen Li, Chunqing Yang, Bingyuan Ji, Yunqing Li, Yingchun Yan, Xinxin Yang, Chunmei Wang, Ting Chen

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Oncolytic viruses: advanced strategies in cancer therapy.Signal transduction and targeted therapy · 2026
    Review
  2. Review
  3. Oncolytic viral vectors in the era of diversified cancer therapy: from preclinical to clinical.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qingjie Xuea Department of Pathogenic Biology , Jining Medical University , Jining , Shandong , China.
Xiuzhen Lia Department of Pathogenic Biology , Jining Medical University , Jining , Shandong , China.
Chunqing Yangb Neurobiology Institute, Jining Medical University , Jining , Shandong , China.
Bingyuan Jib Neurobiology Institute, Jining Medical University , Jining , Shandong , China.
Yunqing Lia Department of Pathogenic Biology , Jining Medical University , Jining , Shandong , China.
Yingchun Yanc School of Mental Health, Jining Medical University , Shandong , China.
Xinxin Yangd School of Clinical College, Jining Medical University , Shandong , China.
Chunmei Wangb Neurobiology Institute, Jining Medical University , Jining , Shandong , China.
Ting Chena Department of Pathogenic Biology , Jining Medical University , Jining , Shandong , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, purified GM-CSF and LMP2A mRNAs were amplified by PCR. Then, the GM-CSF and LMP2A sequences were connected by the polypeptide linker (Gly

Indexed as

AdenoviridaeAnimalsCancer VaccinesCell Line, TumorDisease Models, AnimalGenetic VectorsGranulocyte-Macrophage Colony-Stimulating FactorHEK293 CellsHerpesvirus 4, HumanHumansImmunity, CellularImmunity, HumoralImmunotherapyLymphocytes, Tumor-InfiltratingMiceNeoplasmsCancer VaccinesEBV-associated membrane antigen, Epstein-Barr virusGranulocyte-Macrophage Colony-Stimulating FactorRecombinant Fusion ProteinsViral Matrix ProteinsViral Vaccinesadenovirusfusion gene GC2Arecombinationtumor

Identifiers

PMID28892414
PMCPMC5647964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.