Evidence map›Paper›PMID 28891970›Full record

ReviewInternational journal of molecular sciences2017

The ABCC6 Transporter: A New Player in Biomineralization.

Guillaume Favre, Audrey Laurain, Tamas Aranyi, Flora Szeri, Krisztina Fulop, Olivier Le Saux, Christophe Duranton, Gilles Kauffenstein, Ludovic Martin, Georges Lefthériotis

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Impact of theFrontiers in endocrinology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Frontiers in cell and developmental biology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Guillaume FavreFINSERM, U 1081, Aging and Diabetes Team, Institute for Research on Cancer and Aging of Nice (IRCAN), 06107 Nice, France. avre.g@chu-nice.fr.ORCID 0000-0003-1069-4344
Audrey LaurainNephrology Department, University Hospital, 06107 Nice, France. a.laurain@live.fr.
Tamas AranyiInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1117 Budapest, Hungary. aranyi.tamas@ttk.mta.hu.
Flora SzeriInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1117 Budapest, Hungary. floraszeri@me.com.
Krisztina FulopInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1117 Budapest, Hungary. fulop.krisztina@ttk.mta.hu.
Olivier Le SauxDepartment Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA. lesaux@hawaii.edu.ORCID 0000-0002-5605-3617
Christophe DurantonLaboratory of Physiology and Molecular Medicine (LP2M) UMR CNRS 7073, 06107 Nice, France. duranton@unice.fr.
Gilles KauffensteinUMR CNRS 6015-Inserm 1083, School of Medicine, Bretagne Loire University, 49045 Angers, France. gilles.kauffenstein@gmail.com.
Ludovic MartinUMR CNRS 6015-Inserm 1083, School of Medicine, Bretagne Loire University, 49045 Angers, France. LuMartin@chu-angers.fr.
Georges LefthériotisFaculty of Medicine, University of Nice-Sophia Antipolis, 06107 Nice, France. leftheriotis.g@chu-nice.fr.
Centre National de la Recherche Scientifique · FRInstitute of Molecular Life Sciences · HUUniversity of Hawaiʻi at Mānoa · US

Funding

TRPA1 Physiology in Diabetes, Metabolic Syndrome, and MetabolismP20GM113134 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Kathryn Jaques Schunke · 2017 to 2026
$21.5M
The role of ABCC6 in chronic and acute cardiovascular mineralizationR01HL108249 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI BOISVERT, WILLIAM A, LE SAUX, OLIVIER · 2012 to 2015
$1.4M
NHLBI NIH HHS R01 HL108249NIGMS NIH HHS P20 GM113134
6 · The paper itself

Abstract

Pseudoxanthoma elasticum (PXE) is an inherited metabolic disease with autosomal recessive inheritance caused by mutations in the

Indexed as

AnimalsATP-Binding Cassette, Sub-Family C ProteinsHumansMutationPhosphatesPseudoxanthoma ElasticumVascular CalcificationABCC6 protein, humanATP-Binding Cassette, Sub-Family C ProteinsPhosphatesABC transporterarterial calcificationschronic kidney diseaseinorganic pyrophosphatepseudoxanthoma elasticum

Identifiers

PMID28891970
PMCPMC5618590
OpenAlexW2751563717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.