Evidence map›Paper›PMID 28891965›Full record

ReviewInternational journal of molecular sciences2017

Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.

Ayaka Mizumoto, Shinya Ohashi, Kenshiro Hirohashi, Yusuke Amanuma, Tomonari Matsuda, Manabu Muto

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05261620 (W.I.S.E.-Wine Implementation for Surgical Recovery Enhancement), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05261620 nacompletednot on this mapstarted 2022, after this paper: background citation

W.I.S.E.-Wine Implementation for Surgical Recovery Enhancement

TypeinterventionalSponsorIRCCS San RaffaeleRan2022 to 2025Enrolled132ConditionsQuality of LifeArmsred wine
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ayaka MizumotoDepartment of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. ayaka@kuhp.kyoto-u.ac.jp.ORCID 0000-0002-8279-3360
Shinya OhashiDepartment of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. ohashish@kuhp.kyoto-u.ac.jp.
Kenshiro HirohashiDepartment of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. kenshiro@kuhp.kyoto-u.ac.jp.
Yusuke AmanumaDepartment of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. yusuke12@kuhp.kyoto-u.ac.jp.
Tomonari MatsudaResearch Center for Environmental Quality Management, Kyoto University, Otsu 520-0811, Japan. matsuda.tomonari.8z@kyoto-u.ac.jp.
Manabu MutoDepartment of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. mmuto@kuhp.kyoto-u.ac.jp.
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetaldehyde is a highly reactive compound that causes various forms of damage to DNA, including DNA adducts, single- and/or double-strand breaks (DSBs), point mutations, sister chromatid exchanges (SCEs), and DNA-DNA cross-links. Among these, DNA adducts such as

Indexed as

AcetaldehydeAnimalsCarcinogenesisCarcinoma, Squamous CellDNA DamageEsophageal NeoplasmsEthanolHead and Neck NeoplasmsHumansAcetaldehydeEthanolacetaldehydecancer developmentDNA adductDNA damageDNA repair pathwayesophageal squamous cell carcinomahead and neck squamous cell carcinoma

Identifiers

PMID28891965
PMCPMC5618592
OpenAlexW2752729389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.