Evidence map›Paper›PMID 28891935›Full record

ArticleInternational journal of molecular sciences2017

Alteration of Mammary Gland Development and Gene Expression by In Utero Exposure to Cadmium.

Daniela A Parodi, Morgan Greenfield, Claire Evans, Anna Chichura, Alexandra Alpaugh, James Williams, Kedra C Cyrus, Mary Beth Martin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Environmental exposures, stem cells, and cancer.Pharmacology & therapeutics · 2019
    Review
  11. Review
  12. Article
  13. Melatonin: A Molecule for Reducing Breast Cancer Risk.Molecules (Basel, Switzerland) · 2018
    Review
  14. Estrogen Effects on Wound Healing.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daniela A ParodiDepartments of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC 20007, USA. danielaparodi@yahoo.com.
Morgan GreenfieldDepartment of Oncology, Georgetown University, Washington, DC 20007, USA. meg63@georgetown.edu.
Claire EvansDepartments of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC 20007, USA. claire.evans.07@gmail.com.
Anna ChichuraDepartment of Oncology, Georgetown University, Washington, DC 20007, USA. amc258@georgetown.edu.
Alexandra AlpaughDepartment of Oncology, Georgetown University, Washington, DC 20007, USA. alpaua@gmail.com.
James WilliamsDepartment of Oncology, Georgetown University, Washington, DC 20007, USA. jtwilliams@umc.edu.
Kedra C CyrusDepartment of Oncology, Georgetown University, Washington, DC 20007, USA. kc454@georgetown.edu.
Mary Beth MartinDepartments of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC 20007, USA. martinmb@georgetown.edu.
Georgetown University · USVince Lombardi Cancer Clinic · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
TRAINING GRANT IN TUMOR BIOLOGYT32CA009686 · NCI · GEORGETOWN UNIVERSITY · PI ANNA Tate RIEGEL, DAVID J ROBBINS · 1996 to 2026
$10.8M
Impact of environmental metal/metalloid exposures on mammographic breast density, a marker of breast cancerU01ES026132 · NIEHS · GEORGETOWN UNIVERSITY · PI BYRNE, CELIA, MARTIN, MARYBETH · 2015 to 2019
$4.5M
Arsenite and epigenetic regulation of gene expressionR21ES015160 · NIEHS · GEORGETOWN UNIVERSITY · PI MARTIN, MARYBETH · 2006 to 2007
$421k
NCI NIH HHS P30 CA051008NCI NIH HHS T32 CA009686NIEHS NIH HHS R21 ES015160NIEHS NIH HHS U01 ES026132
6 · The paper itself

Abstract

Environmental exposure to estrogens and estrogen like contaminants during early development is thought to contribute to the risk of developing breast cancer primarily due to an early onset of puberty; however, exposure during key developing windows may also influence the risk of developing the disease. The goal of this study was to ask whether

Indexed as

AnimalsCadmiumCells, CulturedEpithelial CellsEstrogen Receptor alphaFemaleHumansMammary Glands, HumanMaternal ExposurePregnancyPrenatal Exposure Delayed EffectsRatsRats, Sprague-DawleyStem CellsCadmiumEstrogen Receptor alphacadmiumestradiolestrogen receptor-αin uteromammosphere-forming cells

Identifiers

PMID28891935
PMCPMC5618588
OpenAlexW2750749423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.