Evidence map›Paper›PMID 28891457›Full record

SynthesisEpidemiology and infection2017

Current prevalence of chronic hepatitis B and C virus infection in the general population, blood donors and pregnant women in the EU/EEA: a systematic review.

S H I Hofstraat, A M Falla, E F Duffell, S J M Hahné, A J Amato-Gauci, I K Veldhuijzen, L Tavoschi

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 10 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 10 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Estimates of hepatitis B virus prevalence among general population and key risk groups in EU/EEA/UK countries: a systematic review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
  2. Pooled it
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  5. Guideline
  6. Pooled it
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  8. Hepatitis B and C prevalence and incidence in key population groups with multiple risk factors in the EU/EEA: a systematic review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Pooled it
  9. Pooled it
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  11. Trial
  12. MicroRNA-122 as a regulator and biomarker of liver disease.Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  13. Article
  14. Article
  15. Use of the Workbook Method to estimate the prevalence of chronic hepatitis B infections in the European Union and European Economic Area, 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

S H I HofstraatCentre for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.
A M FallaDepartment of Infectious Disease Control,Municipal Public Health Service Rotterdam-Rijnmond,Rotterdam,The Netherlands.
E F DuffellEuropean Centre for Disease Prevention and Control,Stockholm,Sweden.
S J M HahnéCentre for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.
A J Amato-GauciEuropean Centre for Disease Prevention and Control,Stockholm,Sweden.
I K VeldhuijzenCentre for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.
L TavoschiEuropean Centre for Disease Prevention and Control,Stockholm,Sweden.
European Centre for Disease Prevention and Control · SENational Institute for Public Health and the Environment · NLErasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review aimed at estimating chronic hepatitis B (HBV) and C virus (HCV) prevalence in the European Union (EU) and Economic Area (EEA) countries in the general population, blood donors and pregnant women. We searched PubMed©, Embase© and Cochrane Library databases for reports on HBV and HCV prevalence in the general population and pregnant women in EU/EEA countries published between 2005 and 2015. Council of Europe data were used for HBV and HCV blood donor prevalence. HBV general population estimates were available for 13 countries, ranging from 0·1% to 4·4%. HCV general population estimates were available for 13 countries, ranging from 0·1% to 5·9%. Based on general population and blood donor estimates, the overall HBV prevalence in the EU/EEA is estimated to be 0·9% (95% CI 0·7-1·2), corresponding to almost 4·7 million HBsAg-positive cases; and the overall HCV prevalence to be 1·1% (95% CI 0·9-1·4), equalling 5·6 million anti-HCV-positive cases. We found wide variation in HCV and HBV prevalence across EU/EEA countries for which estimates were available, as well as variability between groups often considered a proxy for the general population. Prevalence estimates are essential to inform policymaking and public health practice. Comparing to other regions globally, HBV and HCV prevalence in the EU/EEA is low.

Indexed as

Blood DonorsEuropeEuropean UnionFemaleHepatitis B, ChronicHepatitis C, ChronicHumansPregnancyPregnant PeoplePrevalenceHepatitis Bhepatitis Cprevalencesystematic review

Identifiers

PMID28891457
PMCPMC5647665
OpenAlexW2755192742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.