Evidence map›Paper›PMID 28891318›Full record

ArticleAIDS research and human retroviruses2018

What Would an HIV Cure Mean to You? Qualitative Analysis from a Crowdsourcing Contest in Guangzhou, China.

Alice Zhang, Xin Pan, Feng Wu, Yang Zhao, Fengyu Hu, Linghua Li, Weiping Cai, Joseph D Tucker

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  9. Review
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  13. HIV Cure Research Crowdsourcing: An Author Response.AIDS research and human retroviruses · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Alice Zhang1 School of Medicine, University of Maryland-Baltimore , Baltimore, Maryland.
Xin Pan1 School of Medicine, University of Maryland-Baltimore , Baltimore, Maryland.
Feng Wu1 School of Medicine, University of Maryland-Baltimore , Baltimore, Maryland.
Yang Zhao2 University of North Carolina Project-China , Guangzhou, China .
Fengyu Hu1 School of Medicine, University of Maryland-Baltimore , Baltimore, Maryland.
Linghua Li4 Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University , Guangzhou, China .
Weiping Cai4 Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University , Guangzhou, China .
Joseph D Tucker2 University of North Carolina Project-China , Guangzhou, China .

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Unintended and Intended Implications of HIV Cure: A Social and Ethical AnalysisR01AI108366 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RENNIE, STUART, TUCKER, JOSEPH DAVID · 2013 to 2017
$2.9M
NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI108366
6 · The paper itself

Abstract

Much HIV cure social science research has focused on high-income countries. Local key population perspectives, especially from people living with HIV (PLHIV), are needed in low- and middle-income countries. We organized an open contest soliciting responses from key populations, including PLHIV, about what a cure would mean in their lives. Tailored in-person events and social media were used to engage PLHIV, men who have sex with men (MSM), people who inject drugs, and local residents. We received 471 contributions over 4 months. Our thematic analysis showed that many people perceived that a cure would sterilize HIV and bring about new life for PLHIV. Many individuals believed a cure would decrease PLHIV discrimination and many MSM perceived a cure would decrease MSM discrimination. Some participants noted that a cure could help improve interpersonal relations, particularly with families and partners. Many individuals envisioned HIV cure as a panacea to bring about social stability. Some participants also anticipated changes in attitudes toward sex that may result in increased condomless sex. Our findings suggest a continued need for careful management of patient expectations and community engagement.

Indexed as

CrowdsourcingHIVHIV InfectionsHomosexuality, MaleHumansMaleQualitative ResearchSexual and Gender MinoritiesSexual PartnersChinacrowdsourcingcureHIVmeaning

Identifiers

PMID28891318
PMCPMC5771549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.