ArticleThe Journal of comparative neurology2018
Expression of regulatory genes in the embryonic brain of a lizard and implications for understanding pallial organization and evolution.
Article in The Journal of comparative neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 63 citations in OpenAlex.
- Divergent structural trajectories for pallial regionalization within reptiles reveal conserved evolutionary blueprints.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Sensory maps in the telencephalic pallium of goldfish.Brain structure & function · 2026Article
- Neuroimaging and immunofluorescence of the Pseudopus apodus brain: unraveling its structural complexity.Brain structure & function · 2025Article
- Comparative MRI analysis of the forebrain of three sauropsida models.Brain structure & function · 2024Article
- Spatially resolved cell atlas of the teleost telencephalon and deep homology of the vertebrate forebrain.Communications biology · 2024Article
- Anatomical organization of forebrain circuits in the primate.Brain structure & function · 2023Review
- Molecular biology of serotonergic systems in avian brains.Frontiers in molecular neuroscience · 2023Review
- Adult neurogenesis in the telencephalon of the lizardFrontiers in neuroscience · 2023Article
- Molecular Diversity of Neuron Types in the Salamander Amygdala and Implications for Amygdalar Evolution.Brain, behavior and evolution · 2023Article
- Refocusing neuroscience: moving away from mental categories and towards complex behaviours.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Distinct Subdivisions in the Transition Between Telencephalon and Hypothalamus Produce Otp and Sim1 Cells for the Extended Amygdala in Sauropsids.Frontiers in neuroanatomy · 2022Article
- Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming.Frontiers in cell and developmental biology · 2022Article
- Glutamatergic pathways in the brains of turtles: A comparative perspective among reptiles, birds, and mammals.Frontiers in neuroanatomy · 2022Review
- Development of subdomains in the medial pallium ofFrontiers in neuroanatomy · 2022Article
- Genetically identified neurons in avian auditory pallium mirror core principles of their mammalian counterparts.Current biology : CB · 2021Article
- Social boldness correlates with brain gene expression in male green anoles.Hormones and behavior · 2021Article
- Development of the mouse anterior amygdalar radial unit marked by Lhx9-expression.Brain structure & function · 2021Article
- Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala.Brain structure & function · 2021Article
- Genoarchitectonic Compartmentalization of the Embryonic Telencephalon: Insights From the Domestic Cat.Frontiers in neuroanatomy · 2021Article
- Molecular and cellular evolution of corticogenesis in amniotes.Cellular and molecular life sciences : CMLS · 2020Review
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Authors and funding
4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The comparison of gene expression patterns in the embryonic brain of mouse and chicken is being essential for understanding pallial organization. However, the scarcity of gene expression data in reptiles, crucial for understanding evolution, makes it difficult to identify homologues of pallial divisions in different amniotes. We cloned and analyzed the expression of the genes Emx1, Lhx2, Lhx9, and Tbr1 in the embryonic telencephalon of the lacertid lizard Psammodromus algirus. The comparative expression patterns of these genes, critical for pallial development, are better understood when using a recently proposed six-part model of pallial divisions. The lizard medial pallium, expressing all genes, includes the medial and dorsomedial cortices, and the majority of the dorsal cortex, except the region of the lateral cortical superposition. The latter is rich in Lhx9 expression, being excluded as a candidate of dorsal or lateral pallia, and may belong to a distinct dorsolateral pallium, which extends from rostral to caudal levels. Thus, the neocortex homolog cannot be found in the classical reptilian dorsal cortex, but perhaps in a small Emx1-expressing/Lhx9-negative area at the front of the telencephalon, resembling the avian hyperpallium. The ventral pallium, expressing Lhx9, but not Emx1, gives rise to the dorsal ventricular ridge and appears comparable to the avian nidopallium. We also identified a distinct ventrocaudal pallial sector comparable to the avian arcopallium and to part of the mammalian pallial amygdala. These data open new venues for understanding the organization and evolution of the pallium.
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