Evidence map›Paper›PMID 28890908›Full record

ArticleHealth services research and managerial epidemiology

Validation Study of a Predictive Algorithm to Evaluate Opioid Use Disorder in a Primary Care Setting.

Maneesh Sharma, Chee Lee, Svetlana Kantorovich, Maria Tedtaotao, Gregory A Smith, Ashley Brenton

Open access · goldAbstract read
In one paragraph

Article in Health services research and managerial epidemiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Individualized Prospective Prediction of Opioid Use Disorder.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maneesh SharmaGood Samaritan Hospital, Baltimore, MD, USA.
Chee LeeProove Biosciences Inc, Irvine, CA, USA.
Svetlana KantorovichProove Biosciences Inc, Irvine, CA, USA.
Maria TedtaotaoZoe Family Care, Lynn Haven, FL, USA.
Gregory A SmithRed Pill Medical, Inc, Redondo Beach, CA, USA.
Ashley BrentonProove Biosciences Inc, Irvine, CA, USA.
Lynn University · USMedStar Good Samaritan Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpioid abuse in chronic pain patients is a major public health issue. Primary care providers are frequently the first to prescribe opioids to patients suffering from pain, yet do not always have the time or resources to adequately evaluate the risk of opioid use disorder (OUD). PURPOSE: This study seeks to determine the predictability of aberrant behavior to opioids using a comprehensive scoring algorithm ("profile") incorporating phenotypic and, more uniquely, genotypic risk factors. METHODS AND

resultsIn a validation study with 452 participants diagnosed with OUD and 1237 controls, the algorithm successfully categorized patients at high and moderate risk of OUD with 91.8% sensitivity. Regardless of changes in the prevalence of OUD, sensitivity of the algorithm remained >90%.

conclusionThe algorithm correctly stratifies primary care patients into low-, moderate-, and high-risk categories to appropriately identify patients in need for additional guidance, monitoring, or treatment changes.

Indexed as

addictiongenetic testingopioid use disorderpersonalized medicinepharmacogeneticsprecision medicinepredictive algorithmprimary care

Identifiers

PMID28890908
PMCPMC5574481
OpenAlexW2749354890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.