Evidence map›Paper›PMID 28890789›Full record

ArticleVeterinary record open2017

Evaluation of blood metabolites reflects presence or absence of liver abscesses in beef cattle.

Alaina G C Macdonald, Stéphanie L Bourgon, Rupert Palme, Stephen P Miller, Yuri R Montanholi

Open access · goldAbstract read
In one paragraph

Article in Veterinary record open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  8. The Bovine Metabolome.Metabolites · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Alaina G C MacdonaldOntario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Stéphanie L BourgonDepartment of Animal Science and Aquaculture, Dalhousie University, Truro, NS, B2N 5E3, Canada.
Rupert PalmeDepartment of Biomedical Sciences, Unit of Physiology, Pathophysiology and Experimental Endocrinology, Vetmeduni, Vienna, 1210, Austria.
Stephen P MillerDepartment of Animal Biosciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Yuri R MontanholiDepartment of Animal Science and Aquaculture, Dalhousie University, Truro, NS, B2N 5E3, Canada.
Dalhousie University · CAUniversity of Guelph · CAMODUL University Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver abscesses constitute a prominent concern regarding animal health and profitability of the beef industry. Our objective was to evaluate potential biliary and blood indicators of liver abscesses. Twenty-nine beef bulls (initially averaging 356±70.5 kg and 253±30 days of age) were fed a high-concentrate diet during a performance test of 112 days, during which blood was collected at nine time points spaced 0.5-13 days apart within 56 days before slaughter. At the abattoir, blood and bile were collected and livers were inspected for liver abscesses. Results indicated that liver abscesses are associated with elevated levels of plasma cortisol and aspartate aminotransferase, and decreased levels of albumin, cholesterol and testosterone over the period before slaughter. Based on the blood samples collected during exsanguination, the presence of liver abscesses was associated with lower concentrations of thyroxine, albumin, cholesterol and alkaline phosphatase, and is suggested to be associated with lower blood carbon dioxide (P=0.08) and lower biliary cortisol metabolites (P=0.07). Albumin and cholesterol are established indicators of hepatic function and are consistently related to the presence of liver abscesses. Identifying blood parameters that predict liver abscesses has practical implications for cattle husbandry and for ensuring food safety.

Indexed as

albumincholesterolfeedlothigh-grain diettestosteronethyroxine

Identifiers

PMID28890789
PMCPMC5574433
OpenAlexW2602701178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.